Results 131 to 140 of about 3,597,493 (355)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Assessing the determinants of uptake and hesitancy in accessing COVID 19 vaccines in Nigeria: a scoping review

Frontiers in Health Services
The coronavirus disease (COVID-19) is one of the largest public health threats in recent times, with significant health, economic, and social consequences globally.
Chikezie Ifeanyi, Emmanuel Okechukwu, Olushola Tosin, Ichoku Hyacinth, John Ele-Ojo Ataguba, John Ele-Ojo Ataguba, John Ele-Ojo Ataguba, John Ele-Ojo Ataguba, Grace Njeri Muriithi, Daniel Malik Achala, Elizabeth Naa Adukwei Adote, Chinyere Ojiugo Mbachu, Senait Alemayehu Beshah, Chijioke Osinachi Nwosu, John Thato Tlhakanelo, James Akazili, Nyasha Masuka   +16 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

ASSESSING HEALTHCARE PROVIDERS’ ACCEPTANCE OF THE HOSPITAL MANAGEMENT SYSTEM IN A PRIVATE HOSPITAL IN SELANGOR, MALAYSIA

Global Journal of Public Health Medicine
  Introduction: In the current technological era, the implementation and use of information and communication technology are crucial for productivity and organizational management in the health sector.
Nur Hafizah Sapa, Ruonan Li, Yifei Wang, ZHONGXIN Wang, Zurida Ishak   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Assessment of attitudes and goals regarding cosmetic procedures among individuals aged 18 to 28

Turkderm Turkish Archives of Dermatology and Venereology
Background and Design: The number of cosmetic procedures is increasing, and currently, young people are undergoing more procedures. Personal and social factors underlie this, and social media has been added.
Kadir Küçük, Selda Pelin Kartal
doaj   +1 more source

Determinants of Food Acceptance and Micro-Nutrient Deficiency in Preschoolers: A Case Study of Households from Karachi, Pakistan [PDF]

This study attempts to find out the determinants of food acceptance and micro-nutrient deficiency in preschool children from Karachi, Pakistan. Primary data was collected through survey from 400 households by interviewing and filling up the questionnaire.
Ali, Muhammad, Hasnain, Abid, Subzwari, Zammurud   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

I Cannot Tell a Lie: Emotional Intelligence as a Predictor of Deceptive Behavior [PDF]

, 2019
Research has identified that perceived acceptability and likelihood of lying depend on the type of lie and personality characteristics such as honesty, kindness, assertiveness, and Machiavellianism.
Huffman, Jasmine A.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source