Results 71 to 80 of about 228,055 (288)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Effectiveness of Acceptance and Commitment Therapy on the Marital Satisfaction and Sexual Performance in Couples with Emotional Divorce [PDF]

Iranian Journal of Educational Research, 2023
Objective: The purpose of this study was to examine the impact of acceptance and commitment therapy on marital satisfaction and sexual performance in couples experiencing emotional divorce.
Mohammad Hossein Zebhi Zarchi, Fatemeh Jalayer, Tayebeh Gholamzadeh Bafghi, Elnaz Hajiyousefi, Behnaz Hatamikia, Fattaneh Amirmahmoudi   +5 more
doaj  

Schizophrenia (and other psychotic disorders) cognitive-behaviour therapy research programme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 2006
The present study evaluated the effectiveness of a treatment that combined techniques from Cognitive-Behaviour Therapy (CBT) and Acceptance and Commitment Therapy (ACT) to alleviate the psychological distress and symptom severity resultant from psychotic-
Gillingham, Ruth
core  

Experiences of mindfulness training in living with rheumatic disease: an interpretative phenomenological analysis [PDF]

, 2011
This study examined experiences of Mindfulness training for 5 adults living with Rheumatic Disease. Focus group data was used to explore the experience and impact of Mindfulness training in participants aged between 46 and 69 diagnosed with Psoriatic ...
Hawtin, H, Sullivan, Cath
core   +1 more source

Effects of Mindfulness Practice on Performance and Factors Related to Performance in Long-Distance Running: A Systematic Review [PDF]

, 2020
Fatigue, boredom, pain, performance anxiety, and negative thoughts are challenges characteristic of competitive running. One psychological technique that is gaining support and has been successfully implemented in sport is the practice of mindfulness ...
Corbally, Linda, Fothergill, Melissa A., Wilkinson, Mick   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Efecto de una guía de intervención clínica basada en la Terapia de Aceptación y Compromiso, sobre la flexibilidad psicológica en excombatientes colombianos [PDF]

, 2019
Trabajo de investigaciónEl objetivo de esta investigación fue determinar el efecto de la guía de intervención clínica basada en la Terapia de Aceptación y Compromiso ACT) en el aumento de los procesos de aceptación experiencial, defusión cognitiva ...
Baer, Barnard, Bishop, Brown, Cardaciotto, Davies, Fennell, García-Campayo, Germer, Germer, Gilbert, Gilbert, Gilbert, Goetz, Grossman, Grossman, Gunaratana, Hayes, Jopling, Kabat-Zinn, Kabat-Zinn, Keng, Lama, Lama, Lama, Langer, Lazarus, Mayhew, Neff, Neff, Neff, Neff, Neff, Osho, Perez-Bret, Pos, Sauer, Siegel, Simón, Simón, Sprecher, Teasdale, Thera, Thich Nhat Hanh, Torralba Roselló, Vallejo, Virgili, Vreeland, Watts, Wispé   +49 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Comparison of the effectiveness of cognitive–behavioral therapy and acceptance and commitment therapy on depression symptoms and hypersexual behaviours in patients with sex addiction

مجله علوم روانشناختی, 2021
Background: Numerous studies have addressed the impact of cognitive-behavioral therapy and treatment based on acceptance and commitment to depression. However, there is a research gap between comparing the effectiveness of cognitive-behavioral therapy ...
Reihaneh Firoozikhojastehfar, Karim Asgari, Mehrdad Kalantari, Firoozeh Raisi, Zahra shahvari   +4 more
doaj  

Improvement in Patients’ Ability to Care for Anxiety and Impaired Body Image: A Case Report of Acceptance and Commitment Therapy and Family Psychoeducation

Jurnal Keperawatan Indonesia, 2020
Heart failure and hypertension are non-communicable diseases that are responsible for 70% of deaths worldwide and cause anxiety and impaired body image.
Rasmawati Rasmawati, Budi Anna Keliat, Herni Susanti   +2 more
doaj   +1 more source