ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht +53 more
wiley +1 more source
Comparing the Effectiveness of Acceptance and Commitment Therapy and Schema Therapy in Spirituality and Conflict Resolution Styles of Working Women [PDF]
Objective: The aim of this study is to examine the efficacy of two therapeutic approaches, acceptance and commitment therapy (ACT) and schema therapy in addressing promoting spiritualism and conflict resolution styles among employed women.
Mahboubeh Amouei +2 more
doaj
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Comparison of the effectiveness of cognitive behavioral therapy and acceptance and commitment on the insomnia disorder in the middle-aged [PDF]
Background: Sleep is one of the most important psychological and physiological processes for brain function and mental health that control human health. Sleep quality is essential in middle-aged society, and sleep problems in this society are recognized ...
Zahra Homaie mojaz +2 more
doaj
Introduction: Infidelity is a traumatic event that has many psychological consequences, including psychological distress and regret about choosing a spouse.
Sepideh Haddadi +2 more
doaj +1 more source
Background: Research has shown that positivist psychotherapy leads to marital adjustment and a reduction in the desire for divorce in couples. On the other hand, acceptance and commitment therapy has been effective in reducing issues such as conflict and
Bomyad Jamshidzehi +2 more
doaj
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Comparing the Effectiveness of Acceptance and Commitment Therapy and Self-Regulation Training on Ego Resiliency in Depressed Adolescents [PDF]
Objective: The primary aim of this investigation was to evaluate and compare the efficacy of acceptance and commitment therapy with emotional self-regulation therapy in enhancing the ego resiliency of adolescents experiencing depression in Tehran ...
Negin Vahabi +2 more
doaj
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source

