Results 51 to 60 of about 20,221 (298)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The comparison of the effectiveness of acceptance and commitment therapy (ACT) and imagotherapy on the resilience of married women referring to consulting centers in the city of Tehran

مجله علوم روانشناختی, 2019
Background: Marital conflicts reduce couples’ resilience. But can acceptance and commitment therapy and imagotherapy help improve the resilience of married women referring to consulting centers?
samane nikkhah, masome behboodi, parivash vakili   +2 more
doaj  

Effectiveness of Acceptance& Commitment Therapy on Improving Working Divorced Women's Quality of Life [PDF]

Mağallaẗ Kulliyyaẗ Al-H̲idmaẗ Al-Īğtimāʿiyyaẗ Lil Dirāst wa Al-Buḥūṯ Al-Īğtimāʿiyyaẗ
The current study aimed at  investigating the effectiveness of Acceptance and Commitment Therapy (ACT) on  improving the quality of life for working divorced women.
Ahmed Wagih El-Dessouki El-Morsy, Mohamed Reda Gad Hawass   +1 more
doaj   +1 more source

Kritik Diri dan Kelenturan Psikologis pada Mahasiswa Indonesia : Implikasi Terhadap Intervensi Acceptance and Commitment Therapy (ACT)

Jurnal Paedagogy, 2023
his study aims to examine the relationship between self-criticism and psychological inflexibility as a basis for ACT interventions in college students. The research method used correlation with a quantitative approach.
Diana Syamila, Eka Wahyuni
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The effectiveness of acceptance- and commitment-based therapy on perception of disease in patients with irritable bowel syndrome

International Archives of Health Sciences, 2020
Aims: The purpose of this study was to investigate the effectiveness of acceptance and commitment therapy on perception of disease in patients with irritable bowel syndrome (IBS).
Sedighe Aghalar, Fardin Moradi Manesh, Naser Saraj Khorami, Fariba Hafezi   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Acceptance and Commitment Therapy (ACT) for HIV-infected Hazardous Drinkers: A Qualitative Study of Acceptability [PDF]

Alcoholism Treatment Quarterly, 2018
Alcohol use is a significant problem in HIV care, and clinical trials of alcohol interventions for people living with HIV infection (PLWH) have produced mixed results. The purpose of this qualitative study was to collect preliminary data on the practical feasibility and acceptability of Acceptance and Commitment Therapy (ACT) as a treatment for PLWH ...
Sarah E. Woolf-King, Alan Z. Sheinfil, Jacklyn D. Babowich, Bob Siedle-Khan, Amanda Loitsch, Stephen A. Maisto   +5 more
openaire   +2 more sources

Compassion-Focused Acceptance and Commitment Therapy for Eating Disorders: A Multiple Baseline across Participants Study

, 2019
This study used a multiple baseline across participants design to demonstrate a functional relationship between a compassion-focused acceptance and commitment therapy (ACT) intervention and three participants’ eating disorder (ED) behaviors and values ...
Hill, Mary
core   +1 more source