Results 121 to 130 of about 1,616,125 (301)

On Keynes’s criticism of the Loanable Funds Theory [PDF]

Contemporary monetary theory, by accepting the theses of the Loanable funds theory, distances itself from Keynes, who considered the rate of interest as an exclusively monetary phenomenon, and overlooks the arguments Keynes used, following publication of
Giancarlo Bertocco
core  

Licensed To Kill: A Defense of Vicarious Liability Under the Endangered Species Act [PDF]

, 2014
The Endangered Species Act (ESA) makes it illegal to take an endangered and threatened species by killing, harming, or harassing the animal. Although the classic example of a take is an individual poacher shooting an endangered species, these protected
Damiano, Devon Lea
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Predicting m-health acceptance from the perspective of unified theory of acceptance and use of technology

Scientific Reports
Addressing the growing popularity of mobile health (m-Health) technology in the health industry, the current study examined consumers’ intention and behaviour related to the usage of digital applications based on the unified theory of acceptance and use ...
Marvello Yang, Abdullah Al Mamun, Jingzu Gao, Muhammad Khalilur Rahman, Anas A. Salameh, Syed Shah Alam   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Acceptability judgement tasks and grammatical theory

, 2016
This thesis investigates methodological and statistical issues in acceptability judgement tasks. It compares syntactic author judgements with experimental acceptability data, explores how modality and formality affect judgements of spoken vs written constructions, and evaluates statistical transformations (e.g., Z-scores) for increased analytical power.
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

AI acceptance and Chinese EFL learners’ behavioral engagement with mediating effects of motivation

Scientific Reports
As artificial intelligence (AI) technologies become increasingly integrated into education, understanding how they influence learners’ engagement is essential for effective pedagogy.
Qiufen Wang, Mansour Amini, Ziqiang Fu
doaj   +1 more source