Results 101 to 110 of about 1,616,125 (301)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Fiqhi Validation of the Legal Foundations of the Time Value of Money [PDF]

open access: yesپژوهش‌های فقهی مسائل مستحدثه
Based on the theory of the time value of money, currency possesses a value that changes over time, and at any given moment, its value is affected by a discount rate in subsequent payments or receipts.
Seyyed Sadegh Tabatabaei Nejad   +1 more
doaj   +1 more source

Arithmetic, Set Theory, Reduction and Explanation [PDF]

open access: yes, 2018
Philosophers of science since Nagel have been interested in the links between intertheoretic reduction and explanation, understanding and other forms of epistemic progress.
D’Alessandro, William
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Analytical comparison of Technology Acceptance Model and theory of reasoned action about mobile advertising acceptance

open access: yesتحقیقات بازار یابی نوین, 2014
With the emergence of high speed wireless network technologies and the increasing market penetration of cell phones the global advertising industry’s interest in using this medium as a means of marketing communication is rising.
Mohamad Tabatabaei Nasab   +2 more
doaj  

The Dutch Banking Chipcard Game [PDF]

open access: yes
The banks in the Dutch chipcard market initially agreed on one chipcard system. One system is attractive for companies as well as consumers. Companies, banks and retailers, prevent costs of duplication, while consumers enjoy the benefits of a widespread ...
Hendrikse, G.W.J., Vries, H.J. de
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Immunization effect of inoculation messages: interventions against consensus and misinformation to improve public acceptance of recycled water

open access: yesHumanities & Social Sciences Communications
The global freshwater crisis is accelerating, posing an urgent need for sustainable water solutions. Despite its potential as a viable alternative, recycled water has yet to gain widespread public acceptance. A key barrier is the public’ low intention to
Hanliang Fu   +5 more
doaj   +1 more source

An Analysis of the Influence of Students´ Technological Culture on Their Technology

open access: yes, 2011
decade has raised the interest among the research community on the acceptance and use of these systems by both teachers and students. At first, the implementation of LMS was based on their technical design and the adaptation of the learning processes ...
Dueñas Rugnon, Oscar Lorenzo   +3 more
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

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