Results 81 to 90 of about 1,616,125 (301)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Theoretical Analysis of Acceptance Rates in Multigrid Monte Carlo

, 1991
We analyze the kinematics of multigrid Monte Carlo algorithms by investigating acceptance rates for nonlocal Metropolis updates. With the help of a simple criterion we can decide whether or not a multigrid algorithm will have a chance to overcome critial
A. Hulsebos, G. Mack, G. Mack, G. Mack, G. Parisi, J. Goodman, J. Goodman, J. Goodman, Klaus Pinn, M. Hasenbusch, M. Hasenbusch, M. Hasenbusch, M. L. Laursen, Martin Grabenstein, R. G. Edwards, R. H. Swendsen, S. Gupta, T. Kalkreuter, U. Wolff, U. Wolff   +19 more
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Understanding Technology Acceptance and Use in Social Media Platforms: A Systematic Literature Review and the Development of Research Framework

Journal of Social Computing
The Systematic Literature Review (SLR) presented in the document focuses on the acceptance of social media (SM) platforms, particularly through the lens of the Unified Theory of Acceptance and Use of Technology (UTAUT), Technology Acceptance Model (TAM),
Muhammad Amirul Asyraaf Roslan, Nurul Amelina Nasharuddin, Masrah Azrifah Azmi Murad   +2 more
doaj   +1 more source

K-12 students' online learning motivation in China: An integrated model based on community of inquiry and technology acceptance theory. [PDF]

Educ Inf Technol (Dordr), 2022
Zuo M, Hu Y, Luo H, Ouyang H, Zhang Y.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pengujian Technology Acceptance Model (Tam) dan Theory Planned Behavior (Tpb) [PDF]

, 2010
The purpose of this study is to examine the factors that determine intention of the accounting student to adopt internal software My Quick Accounting System (My QAS) in economic faculty of Islamic University “45” Bekasi.
Lucyanda, J. (Jurica)
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Integration of technology acceptance models and government support to improve digital literacy

Heliyon
Digital domain is important for the expansion of micro and small enterprises but the gap in readiness to accept the technology impacts businesses. Therefore, this research aims to build an integrated model of Technology Readiness Index, Technology ...
Susi Desmaryani, Ahmad Soleh, Irmanelly, Iqra Wiarta   +3 more
doaj   +1 more source

A framework for the adoption and diffusion of Personal Learning Environments in commercial organisations: an exploratory study in the learning and development sector in the UK [PDF]

, 2011
This study presents an exploratory approach to identify the main factors of Personal Learning Environment (PLE) adoption and diffusion within commercial organisations.
Chatterjee, Arunangsu, Law, Effie, Mikroyannidis, Alexander, Owen, Glyn, Velasco, Karen   +4 more
core