Results 71 to 80 of about 6,044,865 (277)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Psychological Contracts and Emotional Labor in the Age of AI: A Moderated Mediation Model

open access: yesBehavioral Sciences
This study examines how employees’ perceptions of transactional and relational psychological contracts influence emotional labor strategies in contemporary work contexts where AI technologies are increasingly present through AI anxiety, general attitudes
Kübra Karakış, Oya Erdil
doaj   +1 more source

Personal autonomy as a key factor of human self-determination

open access: yesSocial Welfare: Interdisciplinary Approach, 2018
The article presents the research on psychological factors of personal autonomy as a self-determination need and as a component of psychological well-being.
Liudmyla Serdiuk   +2 more
doaj   +1 more source

ISRI - Information Systems Research Constructs and Indicators: A Web Tool for Information Systems Researchers

open access: yesJournal of Information Science Theory and Practice, 2021
This paper presents the ISRI (Information Systems Research Indicators) Web tool, publicly and freely available at isri.sciencesphere.org. Targeting Information Systems (IS) researchers, it compiles and organizes IS adoption and use theories/models ...
João Varajão   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A transition process from information systems acceptance to infusion behaviour in online brand communities: A socialization process perspective [PDF]

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Social media such as Facebook, Youtube, Twitter, and online communities plays an important role for knowledge production and diffusion as well as ...
Lim, Jaehoon
core   +4 more sources

Understanding Technology Acceptance and Use in Social Media Platforms: A Systematic Literature Review and the Development of Research Framework

open access: yesJournal of Social Computing
The Systematic Literature Review (SLR) presented in the document focuses on the acceptance of social media (SM) platforms, particularly through the lens of the Unified Theory of Acceptance and Use of Technology (UTAUT), Technology Acceptance Model (TAM),
Muhammad Amirul Asyraaf Roslan   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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