Results 91 to 100 of about 12,183,703 (250)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Path: R:\ETC\80879_DAPL\GIS\DataFiles\ArcDocs\EnvironmentalAssessment\A1_ETC_DAPL_Vicinity.mxd jdringman 12/17/2015 COPYRIGHT ©2015 BURNS & McDONNELL ENGINEERING COMPANY. INC.
Dakota Access, LLC
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Background Gestational Diabetes Mellitus (GDM) contributes to maternal and neonatal complications and is a growing concern in Kenya. The 2-hour oral glucose tolerance test (OGTT) is recommended to diagnose GDM between 24 and 28 weeks of pregnancy, but ...
Rachel Ogumbo +7 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Dakota Access Pipeline Project, Dakota Access, LLC: Hancock County, Illinois
Path: Z:\Clients\ESP\DakotaAccess\84099_ETCDAPLIL\Studies\Geospatial\DataFiles\ArcDocs\Cultural\lndividual\DAPL_IL_Cultural_MississippiRiverHDDLandscape.mxd kdboatright 2/9/2016 11HA978 I 11HA25 Proposed Pipeline CD Archaeological Site Survey Corridor ...
Dakota Access, LLC;
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Dakota Access Pipeline Project, Dakota Access, LLC, cultural avoidance sites, 11MR176, 11MR255
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Dakota Access, LLC;
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

