Results 111 to 120 of about 12,183,703 (250)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

[Figures], Dakota Access Pipeline Project, Dakota Access, LLC, project overview

open access: yes
Path: R:\ETC\80879_DAPL\GIS\DataFiles\ArcDocs\BA_Maps\BA_Fall2015\A01_Pg1_BA_Overview_AIIActionAreas.mxd jdringman 11/4/2015 COPYRIGHT© 2015 BURNS & McDONNELL ENGINEERING COMPANY, INC.
Dakota Access, LLC;
core  

Dakota Access Pipeline Project, Dakota Access, LLC, cultural avoidance sites, Thorp Cemetery

open access: yes
PCN Review Area 82 s j Ji ■k^ ■ •■ ronu-i OO Cjf . o OO Site ID: Thorp Cemetery Site Avoidance Plan Distance to Centerline: 68ft Distance to Workspace: 31ft Notes: Barrier fencing would be installed along the ROW to separate the site from the ...
Dakota Access, LLC;
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Refugee Youth and Migration: Using Arts-Informed Research to Understand Changes in Their Roles and Responsibilities

open access: yesForum: Qualitative Social Research, 2015
This article presents the findings from a community-based qualitative study that utilized an arts-informed method to understand the changes in refugee youth's roles and responsibilities in the family within the (re)settlement context in Canada. The study
Sepali Guruge   +5 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Dakota Access Pipeline Project, Dakota Access, LLC, PCN area review

open access: yes
Path: \\espsrv\Data\Projects\ETC\80879_DAPL\GIS\DataFiles\ArcDocs\Mapbooks\DAPL_IL_PCN_Maps.mxd jdringman 5/2/2015 COPYRIGHT © 2015 BURNS & McDONNELL ENGINEERING COMPANY, INC.
Dakota Access, LLC;
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Author Correction: A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability

open access: yesnpj Vaccines, 2022
Emily A. Voigt   +14 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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