Harnessing and Sharing the Benefits of State Sponsored Research [PDF]
, 2006 In recent years data-sharing has been a recurring focus of struggle within the scientific research community as improvements in information technology and digital networks have expanded the ways that data can be produced, disseminated, and used ...
Eisenberg, Rebecca S., Rai, Arti K.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Biodiversity and international stakes : a question of access [PDF]
This paper examines three main questions: Is it possible to create a market for genetic resources? Is it a perfectly or an imperfectly competitive market?
Trommetter, M.
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The nagoya protocol and biodiversity conservation: legal insights on access and benefit-sharing for medicinal and aromatic plant resources [PDF]
International Journal of Minor Fruits, Medicinal and Aromatic PlantsThis study examines the emergence of a rights-based perspective for biodiversity conservation through the Convention on Biological Diversity, which grants states sovereign rights over natural resources and emphasizes fair and equitable benefit-sharing ...
Shreya Bajpai
doaj +1 more source
Equity in the Pandemic Treaty: Access and Benefit-Sharing as a Policy Device or a Rhetorical Device? [PDF]
J Law Med Ethics, 2023 Hampton AR +3 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Institutionalised Exclusion: The Political Economy of Benefit Sharing and Intellectual Property [PDF]
Law, Environment and Development Journal, 2012 The Nagoya Protocol on Access to Genetic Resources and Benefit Sharing (Protocol) has been hailed as providing unprecedented legal support for indigenous and community control over genetic resources and associated knowledge by ensuring that such groups ...
Simon West
doaj
Digital Sequence Information and the Access and Benefit-Sharing Obligation of the Convention on Biological Diversity. [PDF]
Nanoethics, 2023 Akpoviri FI, Baharum SN, Zainol ZA.
europepmc +1 more source