Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Dual attention-based deep learning with blockchain for multimedia data processing and secure access control in IoHT. [PDF]
Reddy GK +5 more
europepmc +1 more source
Statement Recognition of Access Control Policies in IoT Networks. [PDF]
Ma L, Yang Z, Bu Z, Lao Q, Yang W.
europepmc +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
A privacy preserving medical data management framework using blockchain enabled encrypted role based access control. [PDF]
Taloba AI, Rayan A.
europepmc +1 more source
Evidence based Access Control over Web Services using Multi Security
E. S. Shameem Sulthana, S. Kanmani
openalex +1 more source
32 Open access budget tools for the planning of randomised controlled trials: a scoping review [PDF]
Benjamin Speich +5 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Housing quality as a potential risk factor for locally acquired malaria infection in Swaziland
N. Mkhonta +12 more
doaj +1 more source

