Results 21 to 30 of about 7,459,521 (181)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Event Systems and Access Control [PDF]
, 2006 We consider the interpretations of notions of access control (permissions, interdictions, obligations, and user rights) as run-time properties of information systems specified as event systems with fairness.
Merz, Stephan, Méry, Dominique
core +3 more sources
An Access Control Model for Protecting Provenance Graphs [PDF]
, 2015 Postprin
Chen, Liang +3 more
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Strong and Provably Secure Database Access Control
, 2015 Existing SQL access control mechanisms are extremely limited. Attackers can leak information and escalate their privileges using advanced database features such as views, triggers, and integrity constraints.
Basin, David +2 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Quantum control without access to the controlling interaction [PDF]
, 2001 In our model a fixed Hamiltonian acts on the joint Hilbert space of a quantum system and its controller. We show under which conditions measurements, state preparations, and unitary implementations on the system can be performed by quantum operations on ...
D. Janzing +11 more
core +2 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Low-complexity medium access control protocols for QoS support in third-generation radio access networks [PDF]
, 2005 One approach to maximizing the efficiency of medium access control (MAC) on the uplink in a future wideband code-division multiple-access (WCDMA)-based third-generation radio access network, and hence maximize spectral efficiency, is to employ a low ...
O'Farrell, T., Omiyi, P.
core +1 more source