Results 91 to 100 of about 2,563,364 (305)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Regulation of an Open Access Essential Facility [PDF]
In this paper we consider the problem of regulating an open access essential facility. A vertically integrated firm owns an essential input and operates on the downstream market under the roof of a regulatory mechanism.
Manipushpak Mitra, Axel Gautier
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Access to primary health care relative to need for Indigenous Australians [PDF]
, 2014 This paper describes the development, and presents the results, of an area-based index that measures access to General Practitioners relative to the need for primary health care for both the Indigenous and non-Indigenous populations of Australia ...
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Open access activities in Turkey and the Atatürk University Open Archive System [PDF]
, 2008 Scholarly communication is a process that starts with the establishment of scientific publications and aims to spread them to the end users. In this process, the scientific periodicals are the main communication channels.
Polat, Coşkun +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A probabilistic concept of accessibility for access structures
, 2008 In this paper we introduce the concept of weighted accessibility for access structures. In some sense, it represents a measure of how difficult or how easy is to recover the secret. We give also a numerical measure of accessibility for each participant depending on his position in the access structure.
Amer Ramon, Rafael +2 more
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Saudi Endodontic JournalIntroduction: Guided endodontic access has emerged as a highly precise approach, utilizing cone beam computed tomography (CBCT) imaging and three-dimensional (3D)-printed guides to navigate calcified canals while minimizing unnecessary dentin removal ...
Marco Quintana +3 more
doaj +1 more source