Results 81 to 90 of about 90,234,162 (295)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
SMES' SECTOR ACCESS TO FINANCE: AN OVERVIEW [PDF]
Through their contribution to the creation of added value and new jobs, the small and medium enterprises (SMEs) have a significant role in the economic and social development of a country.
Roman Angela
core
Increasing Access to Rural Finance in Bangladesh : The Forgotten "Missing Middle"
, 2007 Increasing access to rural finance is often the last frontier for financial sector development in developing countries. Financial institutions aiming to operate in rural areas in these countries usually have to
Ferrari, Aurora
core +1 more source
Finance-gender gap: Perceptions of access to finance for female entrepreneurs in Wales
, 2023 Issues on gender, entrepreneurship, and access to finance have been identified as problematic in literature. Previous research on access to finance supports the existence of a gender gap within the small and medium enterprise (SME) sector, with access to
Nigel Brown (15464691) +2 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Access to Finance for MSMEs in Belize: Challenges and Opportunities [PDF]
Belize has grown significantly in the post-pandemic era, but achieving sustainable and robust growth requires structural reforms to enhance private investment as an engine for growth.
Inter-American Development Bank
core +1 more source
The Impact of Access to Finance on the Performance of the SME Sector [PDF]
Ovidius University Annals: Economic Sciences Series, 2021 In this research paper we aimed to analyze the impact of access to finance on the performance of SMEs. The aim of the research is to evaluate empirically and analyze the effects of changes in the macroeconomic environment, in particular the access of ...
Erika-Maria Doaca
doaj
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source