Results 91 to 100 of about 1,521,034 (349)
International Journal for Equity in Health, 2013 BackgroundAccess is central to the performance of health care systems around the world. However, access to health care remains a complex notion as exemplified in the variety of interpretations of the concept across authors.
J. Levesque, M. Harris, G. Russell
semanticscholar +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Improving access to urban and regional early childhood services [PDF]
, 2012 This resource sheet focuses on how to improve access to early childhood services located in metropolitan regions and large country towns where the majority of Indigenous people live.
Vicki-Ann Ware
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Health and education: service providers in partnership to improve mental health
International Journal of Mental Health Systems, 2012 Background Children and adolescents from complex or disadvantaged backgrounds and multiple needs often are reluctant to seek help and this is particularly relevant in the context of mental health difficulties. Further, the complexity of the health system
Eapen Valsamma, Lee Lily, Austin Craig
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Substance Abuse Treatment, Prevention, and PolicyBackground Substance use disorders are prevalent among youth in sub-Saharan Africa (SSA), yet treatment resources are scarce. Peer provider delivered brief interventions (BIs) represent an affordable and potentially scalable strategy for addressing youth
Florence Jaguga +9 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Remittances, Public Health Spending and Foreign Aid in the Access to Health Care Services in Developing Countries [PDF]
The aim of this paper is to analyze the respective impacts of remittances, health aid and public spending on the access to health care services in developing countries. The specific objectives are threefold.
Alassane DRABO, Christian EBEKE
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Report of the Region 5 Pediatric Inpatient Psychiatric Services Implementation Group
, 2007 Title from PDF cover (viewed May 29, 2009).; At head of title: State of Connecticut.; "Prepared for: Cristine A.
Connecticut. Region 5 Pediatric Inpatient Psychiatric Services Implementation Group.
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