Results 71 to 80 of about 96,876,350 (295)

Food insecurity is associated with greater difficulty accessing care among people living with HIV with or without comorbid non-communicable diseases in western Kenya

BMJ Global Health
Introduction The relationship between food insecurity and access to healthcare in low-resource settings remains unclear. Some studies find that food insecurity is a barrier to accessing care, while others report that food insecurity is associated with a ...
Rajesh Vedanthan, Dan N Tran, Juddy Wachira, Catherine Kafu, Marta Wilson-Barthes, Omar Galárraga, Sonak D Pastakia, Manuel Vazquez Sanchez, Jamil Said, Becky Genberg, Mariam Ardehali, Ben Mosong   +11 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Access determinants and use of health services among the elderly

Bioscience Journal, 2017
this study aimed to describe the characteristics related to access to and use of health services, and verify factors associated with the use of services among the elderly.
Darlene Mara dos Santos Tavares, Amanda Queiroz de Souza, Maycon Sousa Pegorari, Nayara Cândida Gomes, Renata Afonso Barcelos, Paula Beatriz de Oliveira   +5 more
doaj   +3 more sources

Effective access to health services: operationalizing universal health coverage

Salud Pública de México, 2015
The right to health and its operational form, as an organized social response to health: the right to health protection, are the mainstay for the global push towards universal health coverage.
Germán Fajardo-Dolci, Juan Pablo Gutiérrez, Sebastián García-Saisó   +2 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Improving access to refractive and eye health services

Community Eye Health Journal, 2016
Avoidable blindness and vision impairment affects 741 million people worldwide. Uncorrected refractive error (URE) is the major cause, accounting for 84% of all cases, or 625 million people. Despite URE being easily detected, measured and corrected, many
Luigi Bilotto, Michael Morton, Luisa Casas Luque, Rob Terry, Judith Stern, Kesi Naidoo   +5 more
doaj  

A qualitative pilot study exploring the acceptability of a peer provider delivered substance use brief intervention from the perspective of youth in Kenya

Substance Abuse Treatment, Prevention, and Policy
Background Substance use disorders are prevalent among youth in sub-Saharan Africa (SSA), yet treatment resources are scarce. Peer provider delivered brief interventions (BIs) represent an affordable and potentially scalable strategy for addressing youth
Florence Jaguga, Matthew C. Aalsma, Leslie A. Enane, Matthew Turissini, Edith Kamaru Kwobah, Edith Apondi, Julius Barasa, Gilliane Kosgei, Yvonne Olando, Mary A. Ott   +9 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source