Results 101 to 110 of about 682,030 (316)
Improving the availability and accessibility of emergency drugs and equipment in the Emergency department of Tikur Anbessa specialized hospital in Addis Ababa, Ethiopia [PDF]
, 2016 Berihu Lemlem
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Discover Applied SciencesThe intensification of global aging and the continuous expansion of the disabled population have put forward an urgent need for their daily safety supervision.
Xinyuan Zhang, Wanbing Shi
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Education SciencesUniversities face a dual challenge: supporting student mental health while equipping staff to respond effectively. To address this, we co-designed and embedded the “You Matter, Prioritize Your Wellbeing” intervention within the university curriculum ...
Lisa Chiang +4 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Improvement of Aminopeptidase Activity of Dizinc(II) Complexes by Increasing Substrate Accessibility [PDF]
, 2011 Md. Jamil Hossain +6 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Inclusivity, Gestalt Principles, and Plain Language in Document Design
In the Library with the Lead Pipe, 2016 In Brief: Good design makes documents easier to use, helps documents stand out from other pieces of information, and lends credibility to document creators.
Jennifer Turner, Jessica Schomberg
doaj