Results 101 to 110 of about 939,166 (317)

Access Across America: Transit 2018 Data

open access: yes, 2018
Downloads are available for individual metropolitan regions, as well as states, open-source Geopackage format. Combined ZIP files containing the data for all 50 metropolitan regions are also available in Geopackage format, and are labeled as "All ...
Murphy, Brendan, Owen, Andrew
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Correction: Revisiting the overlooked role of recycled sewage water in high-income countries in adenoviral outbreaks such as the “2022 pediatric hepatitis’ outbreak”

open access: yesEgyptian Pediatric Association Gazette, 2023
Antoine AbdelMassih   +22 more
doaj   +1 more source

A Systematic Review of Quantum Machine Learning in Education 5.0: Applications and Future Research Directions

open access: yesAlgorithms
Quantum computing is one of the most promising emerging technologies, and quantum machine learning (QML), as one of its key branches, is attracting growing interest for intelligent data processing in education. This study conducted a systematic review of
Jimmy Aurelio Rosales Huamani   +5 more
doaj   +1 more source

Development and Application of an Activity Based Space-Time Accessibility Measure for Individual Activity Schedules [PDF]

open access: yes
Accessibility is an important aspect of human existence impacting on our notion of society equity and justice. It plays an important role in a number of existing theories of spatial and travel behaviour in addition to affecting the rate and the pattern ...
Olu Ashiru, John Polak, Robert B. Noland
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Block-level, non-work accessibility data for planned transitways in the Twin Cities

open access: yes, 2020
The data are organized by scenario then by departure window for a total of 28 scenarios. Each scenario has a Geopackage spatial file which is comprised of result layers for the five destination types studied.
Owen, Andrew, Carlson, Kristin
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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