Results 241 to 250 of about 1,274,900 (310)

Nanoparticles Functionalized with Polymer Brushes for Gene Delivery

open access: yesAdvanced NanoBiomed Research, EarlyView.
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

open access: yesAnimal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng   +7 more
wiley   +1 more source

Standardizing Visualization in Ancient Maya Lidar Research: Techniques, Challenges and Recommendations

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT Airborne laser scanning (ALS, lidar) has become a key method for studying ancient Maya landscapes, offering unprecedented visibility of anthropogenic terrain modifications in densely forested environments. Despite this progress, the visualization of elevation data remains understandardized, with many researchers relying on ad hoc or ...
Žiga Kokalj
wiley   +1 more source

Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities

open access: yesArthritis &Rheumatology, EarlyView.
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley   +1 more source

A Tolerogenic Plasmid Inhibits Autoantibody Production Triggered by Immunization With Human Peptidyl Arginine Deiminase 4

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs). We have previously demonstrated that the human PAD4 (hPAD4) is
Philippe P. Pagni   +10 more
wiley   +1 more source

Gamifying anatomy outreach: An underexplored opportunity

open access: yesAnatomical Sciences Education, EarlyView.
Abstract This article explores the underutilized potential of incorporating gamified approaches into anatomy outreach initiatives. While gamification and game‐based learning approaches have been widely adopted in formal educational settings, there is a surprising lack of research on their application for community‐based public engagement with anatomy ...
Mikaela L. Stiver   +3 more
wiley   +1 more source

Real‐world treatment patterns among patients diagnosed with hormone receptor‐positive metastatic breast cancer in the USA

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clinical guidelines for breast cancer management have evolved in the past decade. However, limited evidence exists regarding uptake of novel drug classes in management of hormone receptor‐positive (HR+) metastatic breast cancer (MBC) in the USA and whether disparities exist by race and ethnicity.
Kexin Zhu   +4 more
wiley   +1 more source

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