Results 181 to 190 of about 68,289 (252)

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Genomic plasticity and mobilome architecture of <i>Vibrio europaeus</i> reveal key mechanisms of evolutionary adaptation. [PDF]

Microb Genom
Rodriguez S, Rey-Varela D, Martinez C, Martinez P, Travers MA, Barja JL, Dubert J.   +6 more
europepmc   +1 more source

Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917

Biotechnology and Bioengineering, EarlyView.
The probiotic E. coli Nissle 1917 was engineered to enable stable and antibiotic free protein expression platforms using native plasmids. Further modification aids in the production of high‐level protein expression for antimicrobial secretion whose activity is comparable to industry standard E. coli BL21.
Halimatun Sakdiah Zainuddin, Sanjeeva Kumar Murali, Thomas J. Mansell   +2 more
wiley   +1 more source

Supplementary data for: Stabilising evolution of carbapenem resistance through core–accessory genome co-adaptation in Acinetobacter baumannii

Ben Pascoe, Evangelos Mourtos, Matthew D. Hitchings, Samuel K. Sheppard   +3 more
openalex   +2 more sources

Defence systems drive accessory genome interactions in Pseudomonas aeruginosa

Chong CE, Weimann A, Agapov A, Fothergill JL, Brockhurst MA, Parkhill J, Floto RA, Szczelkun MD, Westra ER, Multi-Defence Consortium, Baker KS.   +10 more
europepmc   +1 more source

Genome analysis and machine learning-based feature selection strategy reveal potential drug-resistance determinants in <i>Nakaseomyces glabratus</i>. [PDF]

Emerg Microbes Infect
Wang Q, Chen R, Cao X, Zhang H, Yang J, Wang X, Liu Y, Tan X, Liang T, Li R, Wan Z, Wang Y, Liu W.   +12 more
europepmc   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

The poplar pathogen <i>Sphaerulina musiva</i> has a dynamic genome architecture marked by chromosomal inversions and changes in transposable element abundance. [PDF]

Microb Genom
Zaccaron AZ, Lassagne A, Søndreli KL, Sudermann MA, Alcalá Briseño RI, Grünwald NJ, Weisberg AJ, LeBoldus JM.   +7 more
europepmc   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source