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Destruction of Staphylococcus aureus biofilms by combining an antibiotic with subtilisin A or calcium gluconate

open access: yesScientific Reports, 2021
In S. aureus biofilms, bacteria are embedded in a matrix of extracellular polymeric substances (EPS) and are highly tolerant to antimicrobial drugs. We thus sought to identify non-antibiotic substances with broad-spectrum activity able to destroy the EPS
JingJing Liu   +4 more
doaj   +1 more source

VIRULENCE [PDF]

open access: yesEvolution, 1994
Why do parasites harm their hosts? Intuition suggests that parasites should evolve to be benign whenever the host is needed for transmission. Yet a growing theoretical literature offers several models to explain why natural selection may favor virulent parasites over avirulent ones.
openaire   +2 more sources

Multilocus sequence typing of clinical Borreliella afzelii strains: population structure and differential ability to disseminate in humans

open access: yesParasites & Vectors, 2018
Background Lyme borreliosis in humans results in a range of clinical manifestations, thought to be partly due to differences in the pathogenicity of the infecting strain.
Floriane Gallais   +10 more
doaj   +1 more source

A Relevant Wound-Like in vitro Media to Study Bacterial Cooperation and Biofilm in Chronic Wounds

open access: yesFrontiers in Microbiology, 2022
Biofilm on the skin surface of chronic wounds is an important factor in the pathology, inhibiting wound healing. The polymicrobial nature of these infected wounds and bacterial interactions inside this pathogenic biofilm are the keys for understanding ...
Cassandra Pouget   +7 more
doaj   +1 more source

A virulent vasculopathy [PDF]

open access: yesBMJ Case Reports, 2011
Arteriopathy is an uncommon complication of primary varicella zoster virus (VZV) infection in the immunocompetent adult. We report a case of a 39-year-old woman known to be VZV negative prior to the event. She presented to the emergency department having experienced an episode of expressive aphasia and right upper limb paraesthesia lasting 15 min.
Molloy, A.   +5 more
openaire   +3 more sources

Spread of the mcr-1 colistin-resistance gene in Escherichia coli through plasmid transmission and chromosomal transposition in French goats

open access: yesFrontiers in Microbiology, 2023
IntroductionColistin-resistance widely disseminated in food-producing animals due to decades of colistin use to treat diarrhea. The plasmid-borne mcr-1 gene has been extensively reported from bovine, swine and chicken worldwide, but smaller productions ...
Michaël Treilles   +5 more
doaj   +1 more source

Virulence Attributes of Low‐Virulence Organisms [PDF]

open access: yesInfectious Diseases in Obstetrics and Gynecology, 1994
The vast majority of infections involving female pelvic structures arise from organisms that are members of the normal flora. In addition, exogenous organisms that invade through the lower genital tract must interact with organisms that are part of the host′s flora.
openaire   +2 more sources

Antiseptic Agents for Chronic Wounds: A Systematic Review

open access: yesAntibiotics, 2022
In many parts of the world, antiseptic agents remain non-indicated in chronic wound care. In the current context of bacterial resistance to antibiotics and the development of new-generation antiseptic agents, wound antisepsis represents an asset for the ...
Koko Barrigah-Benissan   +5 more
doaj   +1 more source

Bacterial Interactions in the Context of Chronic Wound Biofilm: A Review

open access: yesMicroorganisms, 2022
Chronic wounds, defined by their resistance to care after four weeks, are a major concern, affecting millions of patients every year. They can be divided into three types of lesions: diabetic foot ulcers (DFU), pressure ulcers (PU), and venous/arterial ...
Benjamin A. R. N. Durand   +5 more
doaj   +1 more source

Biofilms in Diabetic Foot Ulcers: Significance and Clinical Relevance

open access: yesMicroorganisms, 2020
Foot infections are the main disabling complication in patients with diabetes mellitus. These infections can lead to lower-limb amputation, increasing mortality and decreasing the quality of life. Biofilm formation is an important pathophysiology step in
Cassandra Pouget   +5 more
doaj   +1 more source

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