Results 41 to 50 of about 483,407 (311)

Adaptation of Staphylococcus aureus in a Medium Mimicking a Diabetic Foot Environment

Toxins, 2021
Staphylococcus aureus is the most prevalent pathogen isolated from diabetic foot infections (DFIs). The purpose of this study was to evaluate its behavior in an in vitro model mimicking the conditions encountered in DFI. Four clinical S.
Cassandra Pouget, Claude-Alexandre Gustave, Christelle Ngba-Essebe, Frédéric Laurent, Emmanuel Lemichez, Anne Tristan, Albert Sotto, Catherine Dunyach-Rémy, Jean-Philippe Lavigne   +8 more
doaj   +1 more source

Susceptibility of Acinetobacter baumannii isolates from different sources to biocides: a matter of biofilm

Antimicrobial Resistance and Infection Control
Acinetobacter baumannii is an opportunistic pathogen causing severe infections in patients residing in intensive care units. The ability of A. baumannii to acquire carbapenem-resistance makes these infections difficult to treat and poses a serious risk ...
Leila Hamze, Estelle Saras, Sana Azaiez, Wejdene Mansour, Jean-Yves Madec, Thibault Destanque, Marisa Haenni, Agnese Lupo   +7 more
doaj   +1 more source

WGS Analysis of Clonal and Plasmidic Epidemiology of Colistin-Resistance Mediated by mcr Genes in the Poultry Sector in Lebanon

Frontiers in Microbiology, 2021
Poultry and poultry meat are important contributors to the global antimicrobial burden. Unregulated and illegal use of extended-spectrum cephalosporins (ESC) in this sector has long been identified as a major cause of massive spread of ESC-resistant ...
Hiba Al-Mir, Hiba Al-Mir, Marwan Osman, Antoine Drapeau, Monzer Hamze, Jean-Yves Madec, Marisa Haenni   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Tobramycin and Amikacin Delay Adhesion and Microcolony Formation in Pseudomonas aeruginosa Cystic Fibrosis Isolates

Frontiers in Microbiology, 2017
Cystic fibrosis (CF) patients are predisposed to chronic colonization of the major airways by Pseudomonas aeruginosa biofilms. Pulmonary infections, involving sessile bacteria, are the main cause of morbidity and mortality.
Elodie Olivares, Elodie Olivares, Stéphanie Badel-Berchoux, Christian Provot, Benoît Jaulhac, Gilles Prévost, Thierry Bernardi, François Jehl   +7 more
doaj   +1 more source

A Genome-Wide Association Study Identifies Genomic Regions for Virulence in the Non-Model Organism Heterobasidion annosum ss [PDF]

, 2013
The dense single nucleotide polymorphisms (SNP) panels needed for genome wide association (GWA) studies have hitherto been expensive to establish and use on non-model organisms.
Brandström Durling, Mikael, Mikael Brandström-Durling, Stenlid, Jan,, Olson, Åke,, Sveriges lantbruksuniversitet., Jan Stenlid (102750), Kerstin Dalman (102738), Himmelstrand, Kajsa,, Himmelstrand, Kajsa, Mårten Lind (102744), Kerstin Dalman, Mårten Lind, Olson, Åke, Lind, Mårten,, Kajsa Himmelstrand (102739), Jan Stenlid, Åke Olson (102741), Stenlid, Jan, Lind, Mårten, Mikael Brandström-Durling (102747), Dalman, Kerstin,, Brandström Durling, Mikael,, Åke Olson, Kajsa Himmelstrand, Dalman, Kerstin   +24 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Assessment of Borrelia miyamotoi in febrile patients and ticks in Alsace, an endemic area for Lyme borreliosis in France

Parasites & Vectors, 2020
Background Borrelia miyamotoi is a relapsing fever Borrelia species transmitted by ticks of the Ixodes ricinus complex. Human disease caused by B. miyamotoi was first described in Russia and later in the USA and Japan.
Pierre H. Boyer, Joris Koetsveld, Laurence Zilliox, Hein Sprong, Émilie Talagrand-Reboul, Yves Hansmann, Sylvie Josiane de Martino, Nathalie Boulanger, Joppe W. Hovius, Benoît Jaulhac   +9 more
doaj   +1 more source

Killing them softly:managing pathogen polymorphism and virulence in spatially variable environments [PDF]

, 2013
Understanding why pathogen populations are genetically variable is vital because genetic variation fuels evolution, which often hampers disease control efforts.
Vale, Pedro F; id_orcid, Vale, Pedro F.
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source