Results 51 to 60 of about 548,625 (304)

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Tobramycin and Amikacin Delay Adhesion and Microcolony Formation in Pseudomonas aeruginosa Cystic Fibrosis Isolates

Frontiers in Microbiology, 2017
Cystic fibrosis (CF) patients are predisposed to chronic colonization of the major airways by Pseudomonas aeruginosa biofilms. Pulmonary infections, involving sessile bacteria, are the main cause of morbidity and mortality.
Elodie Olivares, Elodie Olivares, Stéphanie Badel-Berchoux, Christian Provot, Benoît Jaulhac, Gilles Prévost, Thierry Bernardi, François Jehl   +7 more
doaj   +1 more source

WGS Analysis of Clonal and Plasmidic Epidemiology of Colistin-Resistance Mediated by mcr Genes in the Poultry Sector in Lebanon

Frontiers in Microbiology, 2021
Poultry and poultry meat are important contributors to the global antimicrobial burden. Unregulated and illegal use of extended-spectrum cephalosporins (ESC) in this sector has long been identified as a major cause of massive spread of ESC-resistant ...
Hiba Al-Mir, Hiba Al-Mir, Marwan Osman, Antoine Drapeau, Monzer Hamze, Jean-Yves Madec, Marisa Haenni   +6 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Impact of Antibiotic Therapies on Resistance Genes Dynamic and Composition of the Animal Gut Microbiota

Animals, 2021
Antibiotics are major disruptors of the gastrointestinal microbiota, depleting bacterial species beneficial for the host health and favoring the emergence of potential pathogens. Furthermore, the intestine is a reactor of antibiotic resistance emergence,
Tony Rochegüe, Marisa Haenni, Stanislas Mondot, Chloé Astruc, Géraldine Cazeau, Tristan Ferry, Jean-Yves Madec, Agnese Lupo   +7 more
doaj   +1 more source

Evolution of malaria virulence in cross-generation transmission through selective immune pressure [PDF]

, 2007
Theoretical arguments and some mathematical models of host-parasite coevolution (e.g. [1- 6]) suggest host immunity as the driving source for the evolution of parasite virulence.
David E. Gurarie
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Epidemiological and genomic analysis of Acinetobacter baumannii strains from retailed raw meat

Heliyon
Acinetobacter baumannii causes hospital-acquired infections in human patients with compromised immune system. Strains associated to nosocomial infections are often resistant to carbapenems and belong to few international clones (IC1-11). A.
Leila Hamze, Raquel Garcia-Fierro, Antoine Drapeau, Pauline François, Andrea Endimiani, Jean-Yves Madec, Marisa Haenni, Vincent Perreten, Agnese Lupo   +8 more
doaj   +1 more source

Pathogenic Escherichia coli in Dogs Reveals the Predominance of ST372 and the Human-Associated ST73 Extra-Intestinal Lineages

Frontiers in Microbiology, 2020
Escherichia coli is a ubiquitous commensal and pathogen that has also been recognized as a multi-sectoral indicator of antimicrobial resistance (AMR).
Charlotte Valat, Antoine Drapeau, Stéphanie Beurlet, Véronique Bachy, Henri-Jean Boulouis, Raphaëlle Pin, Géraldine Cazeau, Jean-Yves Madec, Marisa Haenni   +8 more
doaj   +1 more source

TroA of Streptococcus suis is required for manganese acquisition and full virulence [PDF]

, 2011
Streptococcus suis causes infections in pigs and occasionally in humans resulting in 23 manifestations as meningitis, sepsis, arthritis and septic shock. For survival within the 24 host, S. suis requires numerous nutrients including trace metals.
Smith, H.E., Rebel, M.J., Wichers Schreur, P.J., Rebel, J.M.J., van Putten, J.P.M., Jos P. M. van Putten, Johanna M. J. Rebel, Mari A. Smits, Paul J. Wichgers Schreur, Smits, M.A., Hilde E. Smith, Wichgers Schreur, P.J., Putten, J.P.M., van, Dep Infectieziekten Immunologie, Strategic Infection Biology   +14 more
core   +1 more source