Results 61 to 70 of about 483,407 (311)
Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive Escherichia coli [PDF]
, 2023 Enteroinvasive Escherichia coli (EIEC) and Shigella are closely related agents of bacillary dysentery. It is widely viewed that EIEC and Shigella species evolved from E.
Ana Teresa López-Jiménez +8 more
core +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Resistance of Animal Strains of Pseudomonas aeruginosa to Carbapenems
Frontiers in Microbiology, 2017 Carbapenems are major antibiotics reserved to human medicine. This study aimed to investigate the mechanisms of carbapenem resistance of a selection of Pseudomonas aeruginosa veterinary strains from the French network Resapath. Thirty (5.7%) imipenem and/
Marisa Haenni +5 more
doaj +1 more source
Limitation of Screening of Different Variants of SARS-CoV-2 by RT-PCR
Diagnostics, 2021 Since January 2021, the diffusion of the most propagated SARS-CoV-2 variants in France (UK variant 20I/501Y.V1 (lineage B.1.1.7), 20H/H501Y.V2 (lineage B.1.351) and 20J/H501Y.V3 (lineage P.1)) were urgently screened, needing a surveillance with an RT-PCR
Agathe Boudet +4 more
doaj +1 more source
Microbiology Spectrum, 2019 ABSTRACT Staphylococcus aureus is clearly the most pathogenic member of the Staphylococcaceae . This is in large part due to the acquisition of an impressive arsenal of virulence factors that are coordinately regulated by a series of dedicated transcription factors.
openaire +2 more sources
The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus
, 2010 Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H. +7 more
core +1 more source
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
The interplay between mobilome and resistome in Staphylococcus aureus
mBioAntibiotic resistance genes (ARGs) in Staphylococcus aureus can disseminate vertically through successful clones, but also horizontally through the transfer of genes conveyed by mobile genetic elements (MGEs).
Rachel Contarin +5 more
doaj +1 more source
NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
Advanced Science, EarlyView.This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Antibiotics, 2021 Resistances to extended-spectrum cephalosporins (ESC) and colistin are One Health issues since genes encoding these resistances can be transmitted between all sectors of the One Health concept, i.e., human, animal, and the environment.
Josman Dantas Palmeira +3 more
doaj +1 more source