Results 81 to 90 of about 548,625 (304)
Infectious Disease Clinics of North America, 2004 At the close of the 19th century, the germ theory had generated a new understanding of the causes of acute infectious diseases and revealed new directions for study. This understanding contributed to the greatest improvements in health in the history of medicine.
openaire +2 more sources
Studies on the structure, lipid modification and interactions of the virulence-associated proteins of rhodococcus equi [PDF]
, 2014 Rhodococcus equi is a Gram-positive soil organism that causes an aggressive bronchopneumonia in foals and opportunistic infections in immuno-compromised humans.
Okoko, Tebekeme
core
Virulence-associated cell wall synthesis and transport.
, 2017 Virulence-associated cell wall synthesis and transport.
Ashutosh N. Aggarwal (358734) +7 more
core +1 more source
Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections [PDF]
, 2006 The pro-inflammatory cytokine tumour necrosis factor alpha (TNF-alpha) is associated with malaria virulence (disease severity) in both rodents and humans.
Long, G H +19 more
core +1 more source
Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation
Advanced Science, EarlyView.Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi +9 more
wiley +1 more source
Evolutionary trade-offs underlie the multi-faceted virulence of Staphylococcus aureus [PDF]
, 2015 Date of Acceptance: 20/07/2015Bacterial virulence is a multifaceted trait where the interactions between pathogen and host factors affect the severity and outcome of the infection. Toxin secretion is central to the biology of many bacterial pathogens and
Williams, Barnabas +94 more
core +1 more source
Advanced Science, EarlyView.Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park +13 more
wiley +1 more source
The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence genes: response. [PDF]
, 2006 A response to Snyder LA, Saunders NJ: The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence genes.
Hinds Jason +5 more
core +1 more source
Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Advanced Science, EarlyView.Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
, 2008 Streptococcus pneumoniae colonizes the mucin-rich environment of the nasopharynx. As colonization may be the first stage of infection, investigation was carried out as to whether the pneumococcus could utilize mucin as a source of nutrient and whether ...
Manco, Sonia +4 more
core +1 more source