Results 91 to 100 of about 483,407 (311)

CTX-M-15/27-positive Escherichia coli and VIM-2-producing Pseudomonas putida in free-living pigeons (Columba livia) in Tunisia

Journal of Global Antimicrobial Resistance
Objectives: Wild birds are vectors of antimicrobial resistance. Birds living in close contact with humans or other animals, like feral pigeons (Columba livia), might be especially prone to acquire resistance genes such as those encoding extended-spectrum
Meriem Souguir, Pierre Châtre, Antoine Drapeau, Sana Azaiez, Imen Hmidi, Sana Ncir, Agnese Lupo, Jean-Yves Madec, Marisa Haenni, Wejdene Mansour   +9 more
doaj   +1 more source

Evolution of malaria virulence in cross-generation transmission through selective immune pressure

, 2007
Theoretical arguments and some mathematical models of host-parasite coevolution (e.g. [1- 6]) suggest host immunity as the driving source for the evolution of parasite virulence.
David E. Gurarie
core  

Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]

, 2014
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James, Jäger, Franziska, van der Kooi - Pol, Magda, Cargill, James S, Cao, Zhen Ping, van der Kooi-Pol, Magdalena M., Hunter, William N., Palmer, Tracy, Ryan, Robert P., Kneuper, Holger, Twomey, Kate B., Ryan, Robert P, Zoltner, Martin, Twomey, Kate B, Cargill, James S., van Dijl, Jan Maarten, Hunter, William N   +16 more
core   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

The ability to utilize mucin affects the regulation of virulence gene expression in Streptococcus pneumoniae.

, 2008
Streptococcus pneumoniae colonizes the mucin-rich environment of the nasopharynx. As colonization may be the first stage of infection, investigation was carried out as to whether the pneumococcus could utilize mucin as a source of nutrient and whether ...
Manco, Sonia, Kadioglu, Aras, Andrew, Peter W, Yesilkaya, Hasan, Terra, Vanessa S   +4 more
core   +1 more source

Effects of α and β-adrenergic signaling on innate immunity and Porphyromonas gingivalis virulence in an invertebrate model

, 2022
To investigate the role of adrenergic signalling (AS) in the host immune response and Porphyromonas gingivalis virulence, we compared norepinephrine (NE) and isoproterenol (ISO) responses in Galleria mellonella. P.
Stossi, Fabio, Anbinder, Ana Lia, de Barros, Patrícia Pimentel, Garcia, Maíra Terra [UNESP], Barros, Patrícia Pimentel de [UNESP], Moraes, Renata Mendonça, Junqueira, Juliana Campos, Anbinder, Ana Lia [UNESP], Junqueira, Juliana Campos [UNESP], Garcia, Maíra Terra   +9 more
core   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

Adherence to and Invasion of Human Intestinal Cells by Arcobacter Species and Their Virulence Genotypes

, 2013
The genus Arcobacter is composed of 17 species which have been isolated from various sources. Of particular interest are A. butzleri, A. cryaerophilus, and A.
Figueras, MJ, Alkeskas, A, Levican, A, Forsythe, SJ, Gunter, C   +4 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Back to the Origin: blaOXA-204 and blaNDM-1 Genes in Shewanella spp. from a Tunisian River

Microbiology Spectrum, 2022
Sana Ncir, Agnese Lupo, Antoine Drapeau, Pierre Châtre, Meriem Souguir, Sana Azaiez, Jean-Yves Madec, Wejdene Mansour, Marisa Haenni   +8 more
doaj   +1 more source