Results 211 to 220 of about 126,941 (295)
Research advancements and evaluation of multifactor‐induced murine models for gastric cancer
Animal Models and Experimental Medicine, EarlyView.Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang +5 more
wiley +1 more source
Angewandte Chemie International Edition, EarlyView.Pseudotetraivprolide is a new player among the Detoxin/Rimosamide‐like natural products! Its biosynthesis requires FabD from primary metabolism and a PipDFG complex for final‐step acetylation – unlocking its anti‐antibotic activity. Abstract Novel variants of known natural product (NP) classes can provide valuable insights into their biosynthesis ...
Edna Bode +13 more
wiley +1 more source
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
BioEssays, EarlyView.Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years
Clinical Advances in Periodontics, EarlyView.Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay +2 more
wiley +1 more source
Enhanced i‐Motif Stability through Consecutive 2′,2′‐Difluorocytidine Incorporation
Chemistry – A European Journal, EarlyView.Gemcitabine (dFdC) is a unique nucleoside containing two fluorine atoms at the 2′‐position. Using circular dichroism (CD) and nuclear magnetic resonance spectroscopy, we discovered that consecutive dFdC confer remarkable thermal and pH i‐motif stability. In particular, the molecular surface of the fully modified human vertebrate i‐motif structure shows
Arnau Domínguez +7 more
wiley +1 more source
Pan-genome analysis of Ralstonia pseudosolanacearum associated with tobacco bacterial wilt in China. [PDF]
BMC MicrobiolKang J +9 more
europepmc +1 more source
Symbiotic organs shaped by distinct modes of genome evolution in cephalopods [PDF]
, 2019 Minx, Patrick
core +1 more source