Results 221 to 230 of about 126,941 (295)

Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin

Cytoskeleton, EarlyView.
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochore‐associated factor.
Franziska Hentzschel, Friedrich Frischknecht, Matthias Marti   +2 more
wiley   +1 more source

The role of toxin/antidote genes in the maintenance and evolution of accessory chromosomes in Fusarium. [PDF]

Genetics
Sandell L, Forsythe A, Mirandola A, Jorayev S, Urquhart AS, Granger Farbos A, Saupe SJ, Vogan AA.   +7 more
europepmc   +1 more source

Electrochemical Detection of SARS‐CoV‐2 in Saliva Using ZnO Nanorods Functionalized with Gold‐Conjugated Antireceptor‐Binding Domain Antibodies

ChemNanoMat, EarlyView.
An electrochemical immunosensor based on ZnO nanorods functionalized with gold nanoparticle‐conjugated anti‐receptor‐binding domain antibodies enables rapid, noninvasive, and selective detection of SARS‐CoV‐2 in saliva, providing a promising platform for point‐of‐care diagnostic applications.
Fabíola Lelis de Castro, Ana Cristina Honorato Castro‐Kochi, Marcos Roberto de Araújo Silva, Priscila Sabbag Ferreira, Sydney Ferreira Santos, Lídia Maria de Andrade, Mariano Venanzi, Francesca Cavalieri, Mariângela de Oliveira Silva, Isabela Pazotti Daher, Catarina Harumi Oda Ibrahim, Vivian Leite de Oliveira, Jorge Kalil, Tamires Lopes Silva, Silvia Beatriz Boscardin, Wendel Andrade Alves   +15 more
wiley   +1 more source

Defence systems drive accessory genome interactions in Pseudomonas aeruginosa

Chong CE, Weimann A, Agapov A, Fothergill JL, Brockhurst MA, Parkhill J, Floto RA, Szczelkun MD, Westra ER, Multi-Defence Consortium, Baker KS.   +10 more
europepmc   +1 more source

Chromosome-level genome assemblies for the latent pine pathogen, Diplodia sapinea, reveal two accessory chromosomes with distinct genomic features and evolutionary dynamics. [PDF]

G3 (Bethesda)
Shaw PL, Slippers B, Wingfield BD, Laurent B, Penaud B, Wingfield MJ, Crous PW, Bihon W, Duong TA.   +8 more
europepmc   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

Genetic landscape of Borrelia burgdorferi sensu stricto in Canada: a study of genetic diversity. [PDF]

Sci Rep
Mechai S, Feil EJ, Margos G, Ogden NH.
europepmc   +1 more source

Global Stress Responses Identify the Functionally Divergent Regulators Required for Candida auris Commensalism and Pathogenicity

Exploration, EarlyView.
Candida auris is an emerging multidrug‐resistant fungal pathogen that poses a serious global health threat. In our study, we comprehensively delineate both the pan‐genomic and transcriptomic features of C. auris. Intriguingly, our findings reveal an unexpected alkaline pH‐dependent regulation required for C. auris virulence and commensalism mediated by
Chaoyue Xu, Wanxing Xu, Yushun Yuan, Xiaoqing Chen, Ouyang Mo, Zhe Yin, Xinhua Huang, Yuanyuan Wang, Lingfei Hu, Wenwen Xue, Yun Zou, Luyao Zhang, Kunlin Li, Yueru Tian, Jihong Liu, Sichu Xiong, Lei Wu, Yanmei Dong, Guangsheng Chen, Yuping Zhang, Zili Zhou, Ming Guan, Xiaotian Huang, Zhiyi He, Lin Zhong, Lingbing Zeng, Pei Hao, Xiaoqi Zheng, Changbin Chen, Ning‐Ning Liu, Dongsheng Zhou   +30 more
wiley   +1 more source

The <i>Mycobacterium tuberculosis</i> complex pangenome is small and shaped by sub-lineage-specific regions of difference. [PDF]

Elife
Behruznia M, Marin M, Whiley DJ, Farhat MR, Thomas JC, Domingo-Sananes MR, Meehan CJ.   +6 more
europepmc   +1 more source

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

Food Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang, Qi Wu, Mengjia Zhang, Zifu Ni, Pengshuai Zhang, Siyuan Bai, Yibin Wang, Zhongke Sun   +7 more
wiley   +1 more source