Results 251 to 260 of about 126,941 (295)

Short-Read Pangenomes and Their Potential Utility in Population and Conservation Genomics. [PDF]

Mol Ecol Resour
Jeon JY, Allen NM, Black AN, DeWoody JA.
europepmc   +1 more source

Pre‐ and post‐diagnostic meat intake in relation to risk of recurrence and mortality among individuals with stage I–III colorectal cancer

International Journal of Cancer, EarlyView.
What's New? Processed meat and unprocessed red meat intakes are associated with increased colorectal cancer risk. However, evidence on their associations with mortality after colorectal cancer diagnosis is inconsistent. This study examined associations between three meat types, including unprocessed poultry, and the risk of recurrence and all‐cause ...
Anne‐Sophie van Lanen, Dieuwertje E. Kok, Evertine Wesselink, Jeroen W. G. Derksen, Anne M. May, Karel C. Smit, Miriam Koopman, Johannes H. W. de Wilt, Ellen Kampman, Fränzel J. B. van Duijnhoven, on behalf of the COLON and PLCRC studies, Hester van Cruijsen, Jan Willem T. Dekker, Henk K. van Halteren, Johan J.B. Janssen, Maartje Los, Anandi H. W. Schiphorst, Dirkje W. Sommeijer, Dirk J. A. Sonneveld, Mark P. S. Sie, Maarten Vermaas   +20 more
wiley   +1 more source

A comparison by mismatch repair status of real‐world characteristics and outcomes in patients with stage II/III rectal cancer in the Netherlands

International Journal of Cancer, EarlyView.
What's New? Mismatch repair deficiency (dMMR) in rectal cancer is rare, and knowledge about tumor biological behavior, response to treatment, and clinical outcomes in this subset of patients is limited. This nationwide cohort study including 182 patients with dMMR rectal cancer found that they were younger and had more poorly differentiated tumors ...
Renee A. Lunenberg, Ingrid A. Franken, Frederieke H. van der Baan, Femke P. C. Sijtsma, Geraldine R. Vink, Manon N. G. J. A. Braat, Leon M. G. Moons, Miangela M. Lacle, Marloes A. G. Elferink, Susan Boklage, Martijn P. W. Intven, Jamie Garside, Miriam Koopman, Rob van Wuijtswinkel, Jeanine M. L. Roodhart   +14 more
wiley   +1 more source

Gene-level analysis of core carbohydrate metabolism across the Enterobacteriaceae pan-genome. [PDF]

Commun Biol
Näpflin N, Schubert C, Malfertheiner L, Hardt WD, von Mering C.   +4 more
europepmc   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Gap-free comparative genomics uncover virulence factors for Fusarium wilt of watermelons. [PDF]

PLoS Pathog
Ayhan DH, Wang H, Zhang L, Wang G, Yi S, Meng D, Xue L, Geng X, Kong Z, Wang X, Wang L, Yang Q, Wang X, Deng Y, Zhang X, Guo L.   +15 more
europepmc   +1 more source

Plasma proteomic profiling and molecular clustering reveal immune‐defined prognostic subtypes in lung adenocarcinoma

International Journal of Cancer, EarlyView.
What's New? Lung adenocarcinoma shows considerable heterogeneity in disease progression and therapeutic response. Here, the authors analyzed tumor samples through proteomic profiling and applied network‐based clustering. They identified two distinct patient groups with different demographic, clinical, and molecular characteristics.
Ujjwal Neogi, Anoop T. Ambikan, Kati Turkowski, Marc A. Schneider, Vanessa M. Beutgen, Johannes Graumann, Hauke Winter, Marek Bartkuhn, Werner Seeger, Soni S. Pullamsetti, Rajkumar Savai   +10 more
wiley   +1 more source

Comparative Genomic Analysis of <i>Brevibacillus brevis</i>: Insights into Pan-Genome Diversity and Biocontrol Potential. [PDF]

Microorganisms
Yang W, Bao Q, Wang Y, Xiao L, Zeng Z, Zhou L, Yang H.   +6 more
europepmc   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, EarlyView.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

Genomic Profiling Reveals Clinically Relevant Antimicrobial Resistance and Virulence Genes in <i>Klebsiella pneumoniae</i> from Hong Kong Wet Markets. [PDF]

Antibiotics (Basel)
Ngan WY, Rao S, Fung AHY, Habimana O.
europepmc   +1 more source