Results 51 to 60 of about 1,142,037 (288)

Case report: Bilateral renal ectopy with bilateral accessory renal artery and renal pelvis variations

open access: yesTranslational Research in Anatomy, 2023
Introduction: Renal ectopia also known as ectopic kidney is an embryological renal abnormality characterized by abnormal anatomical location of one or both kidneys. Kidneys can vary in number, shape, size, position, rotation and vascularization.
Abdoul Mouïnou Poudiougo   +9 more
doaj   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

open access: yesAdvanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi   +6 more
wiley   +1 more source

Variation in Formation of Renal Artery

open access: yesJournal of College of Medical Sciences-Nepal, 2020
Backgrounds: Renal arteries are two large blood vessels branching laterally from the abdominal aorta just below the superior mesenteric artery. The arteries vary in their level of origin and caliber, obliquity and precise relations.
Ajeevan gautam   +4 more
doaj   +1 more source

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

open access: yesAdvanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu   +15 more
wiley   +1 more source

A solitary precaval right renal artery: A case report

open access: yesClinical Case Reports, 2022
Knowledge of aberrant renal vasculature is critical for preoperative planning of either open or minimally invasive renal surgery. A precaval right renal artery is a rare anatomical variant in which the artery passes anterior to the inferior vena cava(IVC)
Athena Farahzadi   +2 more
doaj   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao   +7 more
wiley   +1 more source

Accessory Renal Arteries: A Cadaveric Study

open access: yesInternational Journal of Biomedical and Advance Research, 2014
Objectives : The precise knowledge of renal vascular pattern is significant in conduct of various renal surgeries, interventional radiology, and urologic procedures. Variations in renal vascularization have assumed greater importance in conservative surgeries; hence the presence of accessory arteries cannot be overlooked during segmental resection ...
Mehta, Gyata, Arole, Vasanti
openaire   +3 more sources

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

open access: yesAdvanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan   +5 more
wiley   +1 more source

Open repair of an abdominal aortic aneurysm in a patient with congenital renal vascular anomalies

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2018
Purpose: The renal vasculature is unique in such a way that each artery behaves as an end artery. The amount of renal damage that can occur by sacrificing these arteries are so unpredictable.
Vineeth Kumar   +3 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

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