Results 61 to 70 of about 904,908 (258)

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

open access: yesAdvanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu   +10 more
wiley   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

open access: yesAdvanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song   +13 more
wiley   +1 more source

Inferior vena cava hypoplasia with right hepatic vein and accessory inferior hepatic vein shunt [PDF]

open access: yes, 2014
Inferior vena cava (IVC) hypoplasia is a rare condition. Venous blood flow is usually provided through collaterals in the azygos or hemiazygos venous systems. However, portosystemic shunts with intrahepatic venous collateral are extremely rare.
Çullu, N.; Department of Radiology, Muğla Sıtkı Koçman University, Faculty of Medicine, Muğla, Turkey   +3 more
core   +2 more sources

A case of an accessory testicular artery [PDF]

open access: yes, 2004
Dissection of an adult male cadaver revealed the presence of an accessory left testicular artery in addition to the normal right and left testicular arteries. In this case the accessory left testicular artery originated from the ventrolateral wall of the
Stewart, D   +1 more
core  

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

open access: yesAdvanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He   +6 more
wiley   +1 more source

Circumaortic left renal vein: a cadaveric case study

open access: yesDiscover Medicine
Circumaortic left renal vein (CLRV) is a rare variation in which two renal veins encircle the aorta prior to draining into the inferior vena cava (IVC) and can be classified into three types based on branching pattern from the renal hilum.
Isabella G. Damjanovic, Irena A. Rebalka
doaj   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

open access: yesAdvanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen   +13 more
wiley   +1 more source

Different techniques of vessel reconstruction during kidney transplantation [PDF]

open access: yesVojnosanitetski Pregled, 2015
Background/Aim. Multiple renal arteries (MRAs) represent a surgical challenge by the difficulty in performing anastomoses, bleeding and stenosis. MRAs should be preserved and special attention should be paid to accessory polar arteries.
Tomić Aleksandar   +6 more
doaj   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao   +7 more
wiley   +1 more source

Pre-operative evaluation of living kidney donors using computerized tomographic angiography (CTA) and conventional angiography: Comparison with intraoperative findings

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2012
This study was undertaken to assess the accuracy of computerized tomographic angiography (CTA) for the evaluation of renal vascular anatomy for pre-operative donor assessment in living kidney transplantation and to compare it with conventional ...
Rahim Taghavi Razavizadeh   +2 more
doaj   +1 more source

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