Results 141 to 150 of about 209,676 (278)

A Bi‐Adjuvant Senolytic Nanovaccine Modulating Dendritic Cell Senescence Ameliorates Aging‐Related Metabolic Dysfunction

Advanced Science, EarlyView.
An active biomaterial‐based bi‐adjuvant nanovaccine restores the immunocompetence of aged dendritic cells to overcome senescent cell tolerance. Accompanied by the downregulation of mitotic kinases Aurka/b and attenuation of senescence‐associated PI3K/AKT phosphorylation, the nanovaccine enhances antigen‐presenting capacity and promotes potent cytotoxic
Qingxu Song, Xiaoxue Du, Wenbo Dong, Ying Wang, Xiaojing Wang, Qiliang Yin   +5 more
wiley   +1 more source

Laparoscopic treatment for an intrapancreatic accessory spleen: A case report. [PDF]

Front Oncol, 2022
Zhang Y, Shi G, Meng L, Wu J, Hu Q, Xv D, Zhang K, Lu Z, Wu J, Jiang K.   +9 more
europepmc   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

Advanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima, Joshua Saylor, Shun Saito, Jinyan Zhou, Haruka Kawano, Shehata Anwar, Haruki Oba, Rachel Huezo, Miyu Okano, Haruki Matsuda, Makoto Kawatani, Kaori Honda, Hiroyuki Osada, Yuta Kikuchi, Masahito Ohue, Masami Ishibashi, Takayoshi Arai, Makoto Inoue, Midori A. Arai   +18 more
wiley   +1 more source

Intrapancreatic accessory spleen mimicking pancreatic malignancy: Diagnostic role of Tc-99m heat-damaged red blood cell scintigraphy. [PDF]

Radiol Case Rep
Yilmaz F, Perktas L.
europepmc   +1 more source

A case of symptomatic intramesenteric accessory spleen: The diagnostic role of contrast-enhanced ultrasound. [PDF]

Ultrasound, 2023
Lepore F, Di Sabatino A, Maconi G.
europepmc   +1 more source

Topology‐Driven X‐Shaped DNA as a cGAS Stimulator to Promote Dendritic Cell Activation and Antitumor Vaccine Efficacy

Advanced Science, EarlyView.
X‐shaped DNA promotes multivalent cGAS assembly and enhances cGAS‐STING signaling. When conjugated with antigenic peptides, the resulting X‐DNA‐based peptide vaccine promotes dendritic cell activation, antigen presentation, and antitumor T‐cell responses.
Jiabei Li, Xuan Wang, Dali Wei, Zhejie Chen, Ziyi Wang, Qing Yu, Yu Yang, Shengpeng Wang   +7 more
wiley   +1 more source

Epidermoid Cysts in an Intrapancreatic Accessory Spleen Mimicking Pancreatic Neoplasms: Two Case Reports and a Literature Review of Japanese Cases. [PDF]

Surg Case Rep
Li X, Hu Q, Takashi Y, Kawata K, Shibuta S, Ando Y, Otsu H, Yonemura Y, Tobo T, Mimori K.   +9 more
europepmc   +1 more source

Accessory Spleen: A Rare and Incidental Finding in the Stomach Wall. [PDF]

Cureus, 2022
Trujillo SG, Saleh S, Burkholder R, Shibli F, Shah B.   +4 more
europepmc   +1 more source

MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation‐Associated Colorectal Cancer by Suppressing the STAT3‐CCL2 Axis and TAM‐Mediated Immunosuppression

Advanced Science, EarlyView.
Our study identifies MAGI3 as an intestinal epithelial gatekeeper that restrains inflammation‐associated colorectal tumorigenesis but is itself suppressed under highly inflammatory conditions. MAGI3 deficiency activates the STAT3‐CCL2 signaling, thereby promoting TAM‐mediated immunosuppression and inflammation‐associated colorectal tumor progression ...
Yumeng Yang, Zhigang Bai, Haibo Wang, Yu Guo, Yan Zhang, Meihan Hu, Shuaikang Fan, Ran Song, Tongmei Zhang, Mengqi Deng, Xiaomei Yang, Zhongtao Zhang, Junqi He   +12 more
wiley   +1 more source

Robot-Assisted Spleen-Preserving Distal Pancreatectomy for an Epithelial Cyst Arising from an Intrapancreatic Accessory Spleen: A Case Report. [PDF]

Surg Case Rep
Ueno M, Hirokawa F, Shigekawa Y, Kimura M, Tabata H, Deguchi M, Kuroiwa H, Hoshida Y, Nakamori M.   +8 more
europepmc   +1 more source