Results 151 to 160 of about 209,676 (278)

Salivary Citrate Deficiency Defines an Endogenous Dentin Remineralization Failure State Through Glandular MT1/2‐Zn2+‐ACO2 Dysregulation

open access: yesAdvanced Science, EarlyView.
Salivary citrate deficiency in early‐stage Sjögren's syndrome accompanies impaired dentin remineralization despite preserved salivary flow and mineral availability. Matched‐ion experiments reveal disrupted mineral organization and reduced dentin recovery at disease‐associated citrate levels.
Ran You   +8 more
wiley   +1 more source

18F‐FGln PET/CT Imaging of Glutamine Uptake Has Potential for Predicting Immunotherapy Response in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
18F‐FGln PET/CT imaging serves as a marker of Gln uptake in hepatocellular carcinoma. Tumors with high Gln uptake drive Treg‐mediated immunosuppression and immune evasion during antitumor immunotherapy. Conversely, tumors with low Gln uptake maintain sufficient Gln in the TME, suppressing Tregs and enabling cytotoxic T cells to inhibit tumor growth ...
Yi Liu   +8 more
wiley   +1 more source

Accessory spleen torsion: a hidden etiology of acute abdominal emergency. [PDF]

open access: yesBJR Case Rep
Sanabria Greciano L   +5 more
europepmc   +1 more source

Survival Results by the Prospectively Determined Clinical Staging for Locally Advanced Gastric Cancer: A Follow‐Up Study of JCOG1302A

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Prospectively determined clinical T and N categories clearly stratified long‐term survival in locally advanced gastric cancer. Patients with cT3N+, cT4aN0, cT4aN+, and cT4b disease showed unfavorable prognosis despite standard treatment. These findings may help optimize patient selection for perioperative treatment strategies.
Tsutomu Hayashi   +19 more
wiley   +1 more source

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir   +6 more
wiley   +1 more source

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