Results 71 to 80 of about 209,676 (278)

Intrapancreatic accessory spleen [PDF]

, 2012
A case of accessory spleen located in the tail of the pancreas in a stillbirth male foetus is reported. The congenital anomaly was revealed at autopsy. The intrapancreatic spleen was well demarcated and was composed of red and white pulp; however, same ...
Fronczek, A., Szumiło, J., Bukharin, S., Burdan, F.   +3 more
core  

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Accessory spleen Aksesuar dalak

, 2004
This study is a case report, who has an accessory spleen. The accessory spleen, which was 3.7 × 3.3 × 1.4 cm, was near the upper pole of the normal spleen in left hypochondriacal region. An artery originating directly from the splenik artery and 1.1mm in
Yalçin, Bülent, OZAN, HASAN, Kocabiyik, Necdet, Tuǧcu, Harun, Kiliç, Cenk   +4 more
core  

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Accessory spleen in a dog: Macroscopic and microscopic findings

Bulgarian Journal of Veterinary Medicine, 2021
Accessory spleens are one or more areas of normal ectopic splenic tissue of variable size supplied by the branches of the splenic artery. A 7 year-old mixed breed male dog was fixed for use as a model in anatomy hall. During the abdominal dissection, the
M. N. Nazem, S. M. Sajjadian, R. Kheirandish , M. A. Shamshirgaran   +3 more
doaj   +1 more source

Accessory spleen in the pelvis

International Journal of Surgery Case Reports, 2015
ABSTRACT INTRODUCTION: Accessory Spleen (AS) is a very rare entity and usually near the spleen’s hilum and in the tail of the pancreas. Pelvis reported as an atypical and a rare localization. AS may be formed during embryonic life, they rise from the left side of the dorsal mesogastrium as a ...
Taşkın, Mine İslimye, Baser, Banu Güleç, Adalı, Ertan, Bülbül, Erdoğan, Uzgören, Engin   +4 more
openaire   +4 more sources

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Accessory spleen presenting as mass in the left upper abdomen

, 2008
An enlarged accessory spleen, 10 x 8 x 6 cm in diameter, adjoining the spleen appearing as a mass on CT and ultrasonography is reported herein. Accessory spleen is an ectopic mass of healthy splenic tissue separate from the main body of the spleen.
Ozturk, Hayrettin, Yagmur, Yusuf
core  

Detection Of Accessory Splenic Tissue On Liver/Spleen Colloid Scan – Another Marvel Of Spect/Ct

Journal of the Pakistan Medical Association
Accessory splenic tissue is common after surgical intervention relating to spleen. However, it can occur by birth and in cases of idiopathic thrombocytopenic purpura (ITP). In ITP, accessory spleen can recur after splenectomy. Imaging modalities like CT
Areeba Amin, Xain Tauqeer, Mairah Razi
doaj   +1 more source