Results 171 to 180 of about 1,039,615 (382)

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

open access: yesAdvanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao   +19 more
wiley   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao   +13 more
wiley   +1 more source

Protocol‐Agnostic Meta Key Distribution for Encrypted Wireless Communications Enabled by Space‐Time‐Coding Metasurface

open access: yesAdvanced Science, EarlyView.
This paper presents a programmable metasurface‐based Meta Key Distribution (MKD) system for secure, protocol‐independent key exchange in indoor wireless settings. By embedding entropy into the wireless channel, it enables lightweight, compatible cryptographic key generation.
Xinyu Li   +7 more
wiley   +1 more source

Environmental safety: modern technologies for detecting accidental oil spills on the sea surface

open access: bronze, 2023
И.Г. Малыгин   +2 more
openalex   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

open access: yesAdvanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang   +21 more
wiley   +1 more source

A Closed‐Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy

open access: yesAdvanced Science, EarlyView.
The work developed a closed‐loop hybrid discovery system to rationally design and predict high‐performance Type I PSs for hypoxic tumor therapy. 664 Potential candidates are identified from a dataset through a support vector machine (SVM) classification model, and two candidates are experimentally verified as Type I PSs, which highlighted the potential
Xia Ling   +9 more
wiley   +1 more source

Accidental Childhood Poisoning

open access: yesJournal of Rawalpindi Medical College, 2014
Background: To study frequency of different poisonings in children in tertiary care hospital. Methods : In this cross sectional study 81 children under 12 years presenting with signs and symptoms of poisoning were included.
Bilal Ahmad
doaj  

Home - About - Disclaimer - Privacy