Results 161 to 170 of about 112,116 (304)

Coral metabolomic diversity is associated with restoration success. [PDF]

Sci Rep
Raker C, Olmeda-Saldaña M, Sedio BE, Prada C.   +3 more
europepmc   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Photosynthetic Responses to Rising CO₂ and Temperature: Mechanisms, Models, and Field Evidence. [PDF]

Glob Chang Biol
Bernacchi CJ, Cavanagh AP.
europepmc   +1 more source

Photoperiodic control of growth, cold acclimation and dormancy development in silver birch (Betula pendula) ecotypes

, 2003
Survival and growth of temperate zone woody plants under changing seasonal conditions is dependent on proper timing of cold acclimation and development of vegetative dormancy, shortening photoperiod being an important primary signal to induce these ...
Palva, ET, Heino, P, Junttila, O, Ernstsen, A, Li, CY, Palva, ET, Univ Helsinki, Dept Biosci, Div Genet, POB 56, FIN-00014 Helsinki, Finland.   +5 more
core  

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Plasticity and evolved changes in mitochondrial physiology across skeletal muscles of high-altitude deer mice (Peromyscus maniculatus). [PDF]

J Exp Biol
Saleem R, Robichaud SG, Lamarre SG, Storz JF, Scott GR.   +4 more
europepmc   +1 more source

OsCPK12-OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice. [PDF]

Adv Sci (Weinh)
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Wang B, Chan A, Fan Y, Wang Y, Xue P, Zhang Y, Zhan X, Wu W, Yu P, Chen D, Fu J, Hong Y, Shen X, Sun L, Zhu A, Cheng S, Liu Q, Cao L.   +17 more
europepmc   +2 more sources

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Thermal acclimation and meal item shape postprandial aerobic performance in the American lobster (<i>Homarus americanus</i>). [PDF]

Conserv Physiol
Yung M, Harrington AM, Kraskura K, Benoit A, Bair H, Schwieterman GD.   +5 more
europepmc   +1 more source

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source