Brassinosteroids negatively regulate barley deacclimation tolerance via modulation of chloroplast gene expression and cell hydration. [PDF]
Pociecha E +5 more
europepmc +1 more source
Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu +6 more
wiley +1 more source
Photoperiod does not affect thermal acclimation of shoot-scale gas exchange but is important for shoot development in cuttings of Norway spruce (Picea abies (L.) H. Karst). [PDF]
Fridell A +3 more
europepmc +1 more source
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao +5 more
wiley +1 more source
Gene Expression Profiling of Transcription Factors and Acclimation-Related Genes in <i>Ribes</i> spp. [PDF]
Zubauskienė AD +4 more
europepmc +1 more source
Wireless blood pressure sensor implantation in sheep: A detailed technique
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer +10 more
wiley +1 more source
Probing the Influence of Paternal Diet on Offspring Neuroanatomy With Mouse MRI. [PDF]
McKnight EGW +7 more
europepmc +1 more source
A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu +6 more
wiley +1 more source
Thermal sensation and comfort responses during repeated exposure to mild heat. [PDF]
Kakitsuba N, Nagano K.
europepmc +1 more source
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny +12 more
wiley +1 more source

