Results 121 to 130 of about 110,579 (344)
Advanced Science, EarlyView.Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Scientific ReportsQuantitative real-time PCR (RT-qPCR) is one of the most accurate methods for gene expression analysis. An important step in such an examination is normalization of the results by the application of appropriate internal control.
Joanna Bocian +2 more
doaj +1 more source
Advanced Science, EarlyView.Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen +8 more
wiley +1 more source
MoleculesThis research concerned the assessment of the utility value of new pea breeding materials intended for registration in the European Union. The research material consisted of sixteen breeding lines and four reference pea varieties.
Anna Fraś +2 more
doaj +1 more source
Effects of dehydration on performance in man: Annotated bibliography [PDF]
A compilation of studies on the effect of dehydration on human performance and related physiological mechanisms.
Greenleaf, J. E.
core +1 more source
Advanced Science, EarlyView.The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian +9 more
wiley +1 more source
The rootstock clones in rubber tree: a new varietal type toward the rejuvenated bi-clone [PDF]
, 2008 Cloning rubber rootstocks by microcutting will remove the genetic variability of the seedling rootstocks; Moreover, it will open the way to the breeding of rootstock clones regarding main challenges as the growth-vigor of the trees, the water stress ...
Carron, Marc-Philippe +6 more
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