Results 121 to 130 of about 90,660 (244)

Establishment of rat model for aspiration pneumonia and potential mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu   +7 more
wiley   +1 more source

Cardiorespiratory fitness and effects of ubiquinol during high-altitude acclimatization and deacclimatization: The SCARF trial. [PDF]

open access: yesiScience
Lv H   +12 more
europepmc   +1 more source

Effects of dehydration on performance in man: Annotated bibliography [PDF]

open access: yes
A compilation of studies on the effect of dehydration on human performance and related physiological mechanisms.
Greenleaf, J. E.
core   +1 more source

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo   +4 more
wiley   +1 more source

CircRNA-miRNA-mRNA regulatory network in high-altitude hypobaric hypoxia-induced hearing impairment and hearing acclimatization. [PDF]

open access: yesBraz J Otorhinolaryngol
Awang D   +8 more
europepmc   +1 more source

Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu   +5 more
wiley   +1 more source

Improved husbandry measures to enhance reproducibility of wound healing studies in the Leprdb/db mouse

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Though the Leprdb/db mouse is a common and well‐studied model of type II diabetes mellitus, there are a few specific guidelines for its husbandry, and wound complications are common. We present a modified husbandry approach for the Leprdb/db mouse that includes increased cage size, decreased housing density, and more frequent cage changes.
May Barakat   +6 more
wiley   +1 more source

Oxygen saturation and acute mountain sickness during repeated altitude exposures simulating high-altitude working schedules. [PDF]

open access: yesSci Rep
Waldner NF   +10 more
europepmc   +1 more source

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