Establishment of rat model for aspiration pneumonia and potential mechanisms
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu+7 more
wiley +1 more source
Cardiorespiratory fitness and effects of ubiquinol during high-altitude acclimatization and deacclimatization: The SCARF trial. [PDF]
Lv H+12 more
europepmc +1 more source
Effects of dehydration on performance in man: Annotated bibliography [PDF]
A compilation of studies on the effect of dehydration on human performance and related physiological mechanisms.
Greenleaf, J. E.
core +1 more source
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo+4 more
wiley +1 more source
CircRNA-miRNA-mRNA regulatory network in high-altitude hypobaric hypoxia-induced hearing impairment and hearing acclimatization. [PDF]
Awang D+8 more
europepmc +1 more source
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu+5 more
wiley +1 more source
Environmental acclimatization of the relatively high latitude scleractinian coral Pavona decussata: integrative perspectives on seasonal subaerial exposure and temperature fluctuations. [PDF]
Zhang M, Huang S, Luo L, Yu K.
europepmc +1 more source
Though the Leprdb/db mouse is a common and well‐studied model of type II diabetes mellitus, there are a few specific guidelines for its husbandry, and wound complications are common. We present a modified husbandry approach for the Leprdb/db mouse that includes increased cage size, decreased housing density, and more frequent cage changes.
May Barakat+6 more
wiley +1 more source
Human acclimatization to altitude. [PDF]
openaire +3 more sources
Oxygen saturation and acute mountain sickness during repeated altitude exposures simulating high-altitude working schedules. [PDF]
Waldner NF+10 more
europepmc +1 more source