Results 141 to 150 of about 128,811 (390)
EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li+15 more
wiley +1 more source
Rye (Secale cereale L.) is one of the most important cereals cultivated in Central and Eastern Europe, valued for its high resistance to environmental stress and high levels of bioactive compounds, such as dietary fiber (DF) and alkylresorcinols (ARR ...
Anna Fraś+3 more
doaj +1 more source
The Danger of Indiscriminate Acclimatization in the Case of Mammals and Birds [PDF]
T. S. Palmer
openalex +1 more source
Metabolite Modulation in Human Plasma in the Early Phase of Acclimatization to Hypobaric Hypoxia
The exposure of healthy subjects to high altitude represents a model to explore the pathophysiology of diseases related to tissue hypoxia. We explored a plasma metabolomics approach to detect alterations induced by the exposure of subjects to high ...
Wen-Ting Liao+11 more
semanticscholar +1 more source
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu+13 more
wiley +1 more source
Background We present a new methylation-sensitive amplified polymorphism (MSAP) approach for the evaluation of relative quantitative characteristics such as demethylation, de novo methylation, and preservation of methylation status of CCGG sequences ...
Piotr T. Bednarek+2 more
doaj +1 more source
Mesophotic coral depth acclimatization is a function of host-specific symbiont physiology
Mesophotic coral ecosystems receive increasing attention owing to their potential as deep coral refuges in times of global environmental change. Here, the mechanisms of coral holobiont photoacclimatization over a 60 m depth gradient in the central Red ...
M. Ziegler+3 more
semanticscholar +1 more source
The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang+16 more
wiley +1 more source
Effect of potato tuber greening on blackleg development by Dickeya solani and Pectobacterium brasiliense [PDF]
Potato (Solanum tuberosum) is a globally important crop, but its production is often threatened by pectinolytic bacteria of genus Pectobacterium and Dickeya, including Pectobacterium brasiliense (Pcb), and Dickeya solani (Ds), which cause two diseases ...
Anna Maria Grupa-Urbańska+2 more
doaj +1 more source
An Essay on Concept and Essencials of Acclimatization
On what conditions should acclimatization-theory be established as a science?. In analyzing the concept of acclimatization scientifically, we are several prevailing interpretation of the concept but cannot find an overal established and accepted interpretation of the concept.
openaire +5 more sources