Results 121 to 130 of about 318,136 (312)
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Wigan and Leigh College: report from the Inspectorate (FEFC inspection report; 90/95 and 15/98) [PDF]
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994-95 and 1997 ...
core
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Flooded with risks or opportunities: Exploring flooding impacts on tourist accommodation [PDF]
Climate and weather-related impacts have become widespread particularly affecting the tourism industry. Flooding has gained research attention over the past decade, since the destruction creates many challenges for tourism businesses.
Mercia Patricia Southon +1 more
doaj
Migrant workers in Rochdale and Oldham [PDF]
This research focuses on the needs and experiences of Central and Eastern European migrants living and working in Rochdale and Oldham. It was commissioned by Oldham Housing Investment Partnership, Oldham Metropolitan Borough Council, Oldham Rochdale ...
Condie, J, Scullion, LC, Steele, A
core +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Blackpool and The Fylde College: report from the Inspectorate (FEFC inspection report; 53/95 and 60/98) [PDF]
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994/95 and 1997 ...
core
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source

