Results 171 to 180 of about 673,880 (301)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Genuine learning biases persist after accounting for temporally decreasing learning rates: Insight from fitting six datasets. [PDF]

Proc Natl Acad Sci U S A
Cecchi R, Palminteri S.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Workshop report-Vulnerability in multi-hazard risks: Addressing its complexity and dynamics. [PDF]

iScience
Santos AP, De Angeli S, Hanf FS, Charlotta M, Nicole VM, Benson V, Marleen Carolijn R, Dunant A, Terzi S, Schweizer PJ, Nunes Carvalho TM, Madruga de Brito M, De Polt K, Šakić Trogrlić R, van den Homberg M.   +14 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Environmental activities of agricultural enterprises: accounting and analytical support [PDF]

Economic Annals-ХХI, 2018
Olesya Tomchuk, Inna Lepetan, Nataliya Zdyrko, Laszlo Vasa   +3 more
openaire   +1 more source

ORGANIZATION OF ACCOUNTING AND ANALYTICAL SUPPORT FOR MANAGING UNCERTAINTY IN IT PROJECTS

Bulletin of the National Technical University "Kharkiv Polytechnic Institute" (economic sciences)
The article substantiates the theoretical and methodological foundations for organizing accounting and analytical support for managing uncertainty in IT projects. It is demonstrated that modern information technology projects are characterized by a highly dynamic environment, evolving requirements, technological complexity, and an increasing role of ...
openaire   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

A critical appraisal of the MIND trial on minimally invasive surgery for intracerebral hemorrhage. [PDF]

Surg Neurol Int
Asghar P.
europepmc   +1 more source

Accounting and analytical support of strategic marketing audit of agricultural sectors business entities [PDF]

, 2016
Kriukova, Irina, Крюкова, Ірина   +1 more
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