Results 81 to 90 of about 8,872,698 (308)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Internal Controls and Financial Reporting Accuracy in Hotels: The Role of Management Commitment and Employee Training

open access: yesSEISENSE Business Review
This study examines the mediating role of management commitment and employee training in the relationship between internal control systems and financial reporting accuracy in the Ghanaian hotel sector. The study uses an exploratory quantitative research
Richmell Baaba Amanamah   +5 more
doaj   +1 more source

Problem-Based Learning [PDF]

open access: yesSocial Sciences and Education Research Review
The primary aim of this study is to provide a deeper insight into the role of Problem-Based Learning in enhancing the Scholarships of Teaching and Learning in accounting education.
Nosihle Veronica Sithole   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Enhancing Students' Higher-Order Thinking Skills Through Accounting Game-Based Learning: A Development and Evaluation Study

open access: yesJournal of Education Technology
The low ability of students to understand the journal material is adjustment, which requires high-level thinking skills (HOTS). Based on the results of the initial survey, as many as 88% of students stated that adjustment journals are very difficult to ...
Nurdian Susilowati   +3 more
doaj   +1 more source

Application of Problem-Based Learning in Accounting to Improve Learner Performance, O.R. Tambo District, Eastern Cape [PDF]

open access: yesJournal of Education and Learning Technology
This study aims to apply problem-based learning methods and investigate the effectiveness of Problem-Based Learning (PBL) in improving learner performance in accounting education within the O.R. Tambo District.
Simkana Baxolise   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Uma análise dos artigos publicados nas revistas Issues in Accounting Education e Journal of Accounting Education no period de 2000 a 2004 [PDF]

open access: yes, 2006
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisO objetivo deste trabalho é conhecer e analisar as características ou aspectos das pesquisas cientificas na área de contabilidade publicadas nos ...
Alexandre, Gislâine Querina
core  

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