Results 91 to 100 of about 4,193,458 (293)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

THE EFFECT OF IMPLEMENTATION OF GOVERNMENT ACCOUNTING STANDARD, GOVERNMENT INTERNAL CONTROL SYSTEM AND ACCOUNTING INFORMATION SYSTEM ON GOOD GOVERNANCE REQUIREMENT WITH THE QUALITY OF FINANCIAL STATEMENT AS MODERATION OF GOVERNMENT WORKING UNIT (SKPA) IN THE GOVERNMENT OF ACEH, INDONESIA

, 2022
Reza Alfarisi, Nadirsyah, Muslim A. Djalil   +2 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Exploring risk resistant banking strategies: implications for sustainable practices

Future Business Journal
The subprime mortgage crisis has sharply traumatized the world financial system and subsequently put a question on the resilience. Even the commercial banks from a strong economy like the USA have experienced abrupt collapse.
Ashik-Uz-Zaman, Md.Thasinul Abedin, Md.Sharif Hossain   +2 more
doaj   +1 more source

The martingale index: A measure of self-deception in betting and finance

Judgment and Decision Making
People who repeatedly risk money, whether they be traders for financial institutions, corporate executives, day traders, or sports bettors, sometimes appear to do better than chance only because the risk of large losses is hidden or overlooked.
Valentin Dimitrov, Glenn Shafer
doaj   +1 more source

Childcare centre for work efficiency of employed parents: perception analysis for business prospects [PDF]

South Asian Journal of Marketing
Purpose – This study aims to explore whether the working parents' perception about the necessity of childcare centres for their work efficiency is associated with their anxieties and concerns related to their dual responsibilities, i.e.
Zarin Khan Moon, Md. Mahedi Hasan
doaj   +1 more source

Local government administration systems and local government accounting information needs: is there a mismatch?

, 2019
After several years of reforms inspired by the New Public Management approach, public sector accounting and performance measurement systems continue to differ among countries.
Sandra Cohen, Francesca Manes Rossi, Eugenio Caperchione, I. Brusca   +3 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source