Results 101 to 110 of about 340,845 (267)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

RPA SOLUTIONS: MANAGING ESSENTIAL TECHNOLOGIES FOR AUTOMATING ORGANIZATIONAL PROCESSES IN THE CONTEXT OF INDUSTRY 4.0 – A CASE STUDY [PDF]

Annals of the University of Craiova: Economic Sciences Series
Due to the rapid evolution of technology in recent years, the way in which everyday activities are approached is constantly changing. A multitude of innovative technologies based on artificial intelligence, various automation solutions such as software ...
Andreea Măldăreanu, Andreea Gabriela Tănase, Raluca-Florentina Crețu, Daniela Țuțui Daniela, Viorel - Costin Banța   +4 more
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Unpacking How Virtual Try-On Technology Influences Consumer Decision-Making in Online Shopping: Insights From Bangladesh

Human Behavior and Emerging Technologies
As virtual technology advances, virtual try-on (VTO) is reshaping e-commerce. Yet, its impact on consumer decision-making remains unclear, highlighting a need for research into its influence on purchasing behavior.
Most. Sadia Akter, Shawrin Ahmed Khan, Nahida Sultana, Md. Tashriful Islam   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Renewable energy, green technology, and natural resource rents in GCC emission mitigation

Discover Sustainability
This study examines the impact of renewable energy (RNEW-ENERGY), green technology, and natural resource rents on carbon emissions in GCC countries. Data was collected from the World Bank development indicators (WDI) and the Organization for Economic ...
Armaya’u Alhaji Sani, Kaneez Fatima Sadriwala, Abdurrahman Adamu Pantamee, Ahmad Yahia Mustafa Al Astal, Elias Abduallah ALShaye   +4 more
doaj   +1 more source

A Perspective on Accounting Information Systems Research [PDF]

Journal of Information Systems, 1999
Uday S. Murthy, Casper E. Wiggins Jr.
openaire   +1 more source