Results 121 to 130 of about 23,655,570 (293)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

THE BENEFITS OF ERP AND RPA INTEGRATION IN THE CONTEXT OF INDUSTRY 4.0: EFFICIENT MASTER DATA MANAGEMENT IN THE SAP SYSTEM [PDF]

Annals of the University of Craiova: Economic Sciences Series
Given the constant development of technology, the digitization of processes is a crucial issue for economic entities that want to increase performance.
Andreea Măldăreanu, Andreea Gabriela Tănase, Cristian Dragoș Țurcan, Raluca-Florentina Crețu, Viorel - Costin Banța   +4 more
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

ASSESSING THE DETERMINANTS OF PERFORMANCE IN WASTE RECYCLING COMPANIES IN THE CONTEXT OF INDUSTRY 4.0: AN ANALYTICAL APPROACH. [PDF]

Annals of the University of Craiova: Economic Sciences Series
This article analyzes the key factors that influence the performance of a production process in recycling plants as well as the unexpected results obtained by integrating advanced technologies.
Andreea Gabriela Tănase, Andreea Măldăreanu, Cristian Dragoș Țurcan, Raluca-Florentina Crețu, Viorel - Costin Banța   +4 more
doaj  

Management accounting practices towards financial performance in manufacturing companies, Bangladesh: Mediating role of rationalized managerial decisions

Social Sciences and Humanities Open
The aim of this study is to analyze how management accounting practices affect the financial performance of manufacturing companies in Bangladesh, taking into account the potential influence of rationalized managerial decision-making.
Fahmida Begum, Md. Musfiqur Rahman
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

RPA SOLUTIONS: MANAGING ESSENTIAL TECHNOLOGIES FOR AUTOMATING ORGANIZATIONAL PROCESSES IN THE CONTEXT OF INDUSTRY 4.0 – A CASE STUDY [PDF]

Annals of the University of Craiova: Economic Sciences Series
Due to the rapid evolution of technology in recent years, the way in which everyday activities are approached is constantly changing. A multitude of innovative technologies based on artificial intelligence, various automation solutions such as software ...
Andreea Măldăreanu, Andreea Gabriela Tănase, Raluca-Florentina Crețu, Daniela Țuțui Daniela, Viorel - Costin Banța   +4 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

National Child Care Information: final report on options for systems development and implementation

, 2002
This report addresses the final phase of the Consultancy Project on National Child Care Information (Phase IV). This consultancy was commissioned by the Steering Group on Child Care Information which was established by the Department of Health and ...
Social Information Systems Ltd
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source