Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
THE BENEFITS OF ERP AND RPA INTEGRATION IN THE CONTEXT OF INDUSTRY 4.0: EFFICIENT MASTER DATA MANAGEMENT IN THE SAP SYSTEM [PDF]
Annals of the University of Craiova: Economic Sciences SeriesGiven the constant development of technology, the digitization of processes is a crucial issue for economic entities that want to increase performance.
Andreea Măldăreanu +4 more
doaj
The interplay of uncertainty, structure and trust on the diffusion of management accounting and control systems: An agent based modeling approach [PDF]
This study attempts to investigate the interplay of uncertainty, structure and trust on the diffusion of a subset of management information systems, namely management accounting and control systems.
Bertrand Masquefa, Pierre Teller
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
ASSESSING THE DETERMINANTS OF PERFORMANCE IN WASTE RECYCLING COMPANIES IN THE CONTEXT OF INDUSTRY 4.0: AN ANALYTICAL APPROACH. [PDF]
Annals of the University of Craiova: Economic Sciences SeriesThis article analyzes the key factors that influence the performance of a production process in recycling plants as well as the unexpected results obtained by integrating advanced technologies.
Andreea Gabriela Tănase +4 more
doaj
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
RPA SOLUTIONS: MANAGING ESSENTIAL TECHNOLOGIES FOR AUTOMATING ORGANIZATIONAL PROCESSES IN THE CONTEXT OF INDUSTRY 4.0 – A CASE STUDY [PDF]
Annals of the University of Craiova: Economic Sciences SeriesDue to the rapid evolution of technology in recent years, the way in which everyday activities are approached is constantly changing. A multitude of innovative technologies based on artificial intelligence, various automation solutions such as software ...
Andreea Măldăreanu +4 more
doaj
A Comparison of Information Systems Coverage in the CPA, CIA and CMA Examinations for the Period 1987-1991 [PDF]
, 1997 In recent years, three major accounting professional organizations, the American Institute of Certified Public Accountants (AICPA), Institute of Management Accountants (IMA) and Internal Auditors Institute (IIA) have considered and issued statements on ...
Akers, Michael D., Doney, Lloyd D.
core +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source