Results 91 to 100 of about 1,766,094 (309)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

SYSTEMS DESIGN PROCEDURES FOR FARM ACCOUNTING [PDF]

open access: yes
This paper presents a conceptual framework, known as systems development, for designing, selecting, and evaluating information systems. Techniques are developed that aid farm managers in choosing an accounting system.
Schnitkey, Gary D., Sonka, Steven T.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Pengaruh Good Corporate Governance, Intellectual Capital Dan Kinerja Lingkungan Terhadap Nilai Perusahaan(Studi empiris pada perusahaan yang terdaftar di Bursa Efek Indonesia periode 2013-2015) [PDF]

open access: yes, 2018
The purpose of this research to examine and analyze of the involvement of users in the development system, training and education programs, and top management support on the performance of accounting information systems.
, Dr. Noer Sasongko, S.E, M.Si, Ak, CA   +1 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Diagnosing performance management and performance budgeting systems: A case study of the U.S. Navy [PDF]

open access: yes, 2009
We present here a case study of an organization within the U.S. Navy that created a new organizational construct and performance management system. We explore the issues faced by naval leaders as they attempt to use their performance information to make ...
Candreva, Philip J, Webb, Natalie J
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Exploring risk resistant banking strategies: implications for sustainable practices

open access: yesFuture Business Journal
The subprime mortgage crisis has sharply traumatized the world financial system and subsequently put a question on the resilience. Even the commercial banks from a strong economy like the USA have experienced abrupt collapse.
Ashik-Uz-Zaman   +2 more
doaj   +1 more source

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