Results 21 to 30 of about 198,146 (305)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A national cross-sectional study on the knowledge and attitude of nurses towards prevention of pressure injury and their relationship with its prevalence

BMC Nursing
Background Pressure injuries can greatly affect a patient’s health, safety, and quality of life. The knowledge and attitudes of nurses towards preventing pressure injuries are vital for providing safe, high-quality healthcare.
Talal ALFadhalah, Marjan Lari, Gheed Al Salem, Shaimaa Ali, Hamad Al Kharji, Hossam Elamir   +5 more
doaj   +1 more source

Proposal for a graded approach to disclosure of interests in accredited CME/CPD [PDF]

Journal of European CME, 2015
Disclosing conflicts of interest (COIs) is an important step in the management of COIs and is considered to be crucial to the trustworthiness of presenters. There are significant variations in disclosure procedures regarding the following:a.
Reinhard Griebenow, Craig Campbell, Amir Qaseem, Sean Hayes, Jennifer Gordon, Lampros Michalis, Heinz Weber, Eugene Pozniak, Robert Schäfer   +8 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Prevalence of pressure injury on the medical wards of public general hospitals in Kuwait: a national cross-sectional study

BMC Health Services Research
Background Pressure injury is a severe problem that can significantly impact a patient’s health, quality of life, and healthcare expenses. The prevalence of pressure injuries is a widely used clinical indicator of patient safety and quality of care. This
Talal ALFadhalah, Marjan Lari, Gheed Al Salem, Shaimaa Ali, Hamad Al Kharji, Hossam Elamir   +5 more
doaj   +1 more source

Survey on the Construction Status of Forensic Virtual Autopsy Laboratory and the Applicability of Laboratory Accreditation

Fayixue Zazhi, 2023
ObjectiveTo survey the development status and actual needs of virtual autopsy technology in China and to clarify the applicability of forensic virtual autopsy laboratory accreditation.MethodsThe questionnaire was set up included three aspects： （1） the ...
GAO Jun-wei, LU Yang, LI Yan-jun, ZOU Dong-hua, HE Guang-long, WANG Yan-bin   +5 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Kinetics‐Controlled Architecture of Binder‐Free Organic Electrodes for Enhanced Ion Transport

Advanced Functional Materials, EarlyView.
Pulse reverse electrodeposition controls nucleation and growth to create hierarchically porous Py‐derived oligomeric electrodes with enhanced ionic accessibility and reduced transport resistance. The resulting binder‐free architectures translate these transport advantages into practical sodium‐storage functionality.
Satendra Kumar, María del Carmen Giménez‐López   +1 more
wiley   +1 more source