Results 201 to 210 of about 387,146 (299)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Coastline Change Surround Sekampung River Estuary Estimated by Geographic Information System Technique

open access: yesJournal of Tropical Soils, 2011
Surround a big river estuary coastline has a dynamic characteristic and change along a period of time, because of a natural process and/or it is accelerated by human activities.
Fahri, Tamaluddin Syam
doaj  

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Bondi-like Accretion Flow Dynamics: The Role of Gravitational Potential [PDF]

open access: yesarXiv
The formation of massive black holes and their coevolution with host galaxies are pivotal areas of modern astrophysics. Spherical accretion onto a central point mass serves as a foundational framework in cosmological simulations, semianalytical models, and observational studies. This work extends the classical spherical accretion model by incorporating
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Carboniferous-Permian magmatism and associated mineralization (Magnitogorsk and East Uralian megazones Southern Urals)

open access: yesЛитосфера, 2016
The South-Ural accretion-collision fold belt began to form at the final stage of the island-arc development of the Urals. This process correlates in time with the Famennian and Early Tournasian. During the Carboniferous, the subsequent inversion from the
D. N. Salikhov   +3 more
doaj  

Optical Variability of Active Galactic Nuclei

open access: yesFrontiers in Astronomy and Space Sciences, 2017
Szymon Kozłowski
doaj   +1 more source

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