Results 181 to 190 of about 26,045 (258)
Direct evidence for magnetohydrodynamic disk winds driving rotating outflows in protostar HOPS 358. [PDF]
Kim CH +6 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Putative Prebiotics Can Disrupt 3D Architecture and Modulate the Microbial Population to Prevent Cariogenic Biofilm Build-Up In Vitro. [PDF]
de Figueiredo VSA +8 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The late formation of chondrites as a consequence of Jupiter-induced gaps and rings. [PDF]
Srivastava B, Izidoro A.
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Analysis of galloping response in ice-coated transmission conductors under wind loads. [PDF]
Wu S, Liu H, Wang Y, Wang Y.
europepmc +1 more source
Planetesimal Accretion under a Realistic Accretion Condition
学位の種別: 課程博士 審査委員会委員 : (主査)東京大学准教授 藤井 通子, (副査)東京大学教授 相川 裕理, 東北大学教授 田中 秀和, 神戸大学教授 大槻 圭史, 東京大学教授 深川 ...
openaire
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source

